Evidence map›Paper›PMID 26153567›Full record

ArticleThe Analyst2015

Lifetimes and stabilities of familiar explosive molecular adduct complexes during ion mobility measurements.

Alan McKenzie-Coe, John Daniel DeBord, Mark Ridgeway, Melvin Park, Gary Eiceman, Francisco Fernandez-Lima

Abstract read
In one paragraph

Article in The Analyst, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Validation of Calibration Parameters for Trapped Ion Mobility Spectrometry.Journal of the American Society for Mass Spectrometry · 2019
    Article
  4. Evidence of Cis/Trans-Isomerization at Pro7/Pro16 in the Lasso Peptide Microcin J25.Journal of the American Society for Mass Spectrometry · 2019
    Article
  5. Towards Discovery and Targeted Peptide Biomarker Detection Using nanoESI-TIMS-TOF MS.Journal of the American Society for Mass Spectrometry · 2018
    Article
  6. Article
  7. Article
  8. Article
  9. Structures of the kinetically trapped i-motif DNA intermediates.Physical chemistry chemical physics : PCCP · 2016
    Article
  10. Towards the Analysis of High Molecular Weight Proteins and Protein complexes using TIMS-MS.International journal for ion mobility spectrometry : official publication of the International Society for Ion Mobility Spectrometry · 2016
    Article
  11. Isomer Separation of Polybrominated Diphenyl Ether Metabolites using nanoESI-TIMS-MS.International journal for ion mobility spectrometry : official publication of the International Society for Ion Mobility Spectrometry · 2016
    Article
  12. Article
  13. Fundamentals of Trapped Ion Mobility Spectrometry Part II: Fluid Dynamics.Journal of the American Society for Mass Spectrometry · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alan McKenzie-CoeDepartment of Chemistry and Biochemistry, Florida International University, Miami, FL 33199, USA. fernandf@fiu.edu.
John Daniel DeBord
Mark Ridgeway
Melvin Park
Gary Eiceman
Francisco Fernandez-Lima

Funding

Mass Spectrometry based molecular imaging of native biological nanodomainsR00GM106414 · NIGMS · FLORIDA INTERNATIONAL UNIVERSITY · PI FERNANDEZ-LIMA, FRANCISCO · 2012 to 2014
$731k
NIGMS NIH HHS R00 GM106414NIGMS NIH HHS R00GM106414
6 · The paper itself

Abstract

Trapped ion mobility spectrometry coupled to mass spectrometry (TIMS-MS) was utilized for the separation and identification of familiar explosives in complex mixtures. For the first time, molecular adduct complex lifetimes, relative stability, binding energies and candidate structures are reported for familiar explosives. Experimental and theoretical results showed that the adduct size and reactivity, complex binding energy and the explosive structure tailor the stability of the molecular adduct complex. The flexibility of TIMS to adapt the mobility separation as a function of the molecular adduct complex stability (i.e., short or long IMS experiments/low or high IMS resolution) permits targeted measurements of explosives in complex mixtures with high confidence levels.

Indexed as

Drug StabilityExplosive AgentsIon ExchangeReproducibility of ResultsExplosive Agents

Identifiers

PMID26153567
PMCPMC4516649

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.