ArticleJapanese journal of radiology2015
Multicentre study of 18F-FDG-PET/CT prostate incidental uptake.
Article in Japanese journal of radiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prostatic incidental uptake on PET/CT: an updated systematic review and meta-analysis of prevalence and malignancy risk.Frontiers in oncology · 2026Pooled it
- Beyond the Primary Tumor: Malignancy Risk and Evaluation Strategies forMolecular imaging and radionuclide therapy · 2026Article
- Definitions of Incidental [Diagnostics (Basel, Switzerland) · 2024Review
- Unexpected focal fluorodeoxyglucose uptake in main organs; pass through or pass by?World journal of clinical cases · 2024Review
- The risk of prostate cancer on incidental finding of an avid prostate uptake on 2-deoxy-2-[Asian journal of urology · 2024Article
- Cancer of unknown primary eventually diagnosed as poorly differentiated prostate cancer: a case report.Journal of medical case reports · 2023Article
- Significance of incidental focal fluorine-18 fluorodeoxyglucose uptake in colon/rectum, thyroid, and prostate: With a brief literature review.World journal of clinical cases · 2022Article
- Incidentalomas of the prostate detected by 18-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2020Article
- Evaluation of Blood Parameters Alteration Following Low-dose Radiation Induced by Myocardial Perfusion Imaging.Journal of biomedical physics & engineering · 2018Article
- Evidence-based management of incidental focal uptake of fluorodeoxyglucose on PET-CT.The British journal of radiology · 2018Review
- 18F-FDG PET/CT in primary brain lymphoma.Journal of neuro-oncology · 2018Article
- Case: Incidental 18F-fluorodeoxyglucose-positron emission tomography/computed tomography prostate uptake: How should these patients be managed?Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2017Article
- Update on advances in molecular PET in urological oncology.Japanese journal of radiology · 2016Review
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimThe purpose of our study was to establish the prevalence and pathological nature of fluorine-18-fluorodeoxyglucose (18F-FDG) prostate incidental uptake (PIU) among patients studied for non-prostate-malignant purposes in three nuclear medicine centres.
methodsWe retrospectively evaluated 20,422 scans performed on male patients; all patients underwent 18F-FDG-PET/CT for purposes not related to prostate disease.
resultsAmong 20,422 patients PIU was identified for 280 (1.4 %) with an average age of 70 ± 10.7 years. Sixty-three of the 280 patients with PIU (22.5 %) underwent PSA dosage and biopsy to determine the nature of the incidental uptake. Thirty-five of the 63 (55.5 %) PIU were malignant whereas 28/63 (44.5 %) were benign. The average value of PSA for patients with benign PIU was 3.7 ± 2.8 ng/ml whereas it was 7.8 ± 8.2 ng/ml in patients with malignant PIU; this difference was statistically significant. For malignant lesions, the average lesion-to-liver SUVmax ratio was 2.9 ± 2.5 and the average lesion-to-blood-pool SUVmax ratio was 3.7 ± 2.5. For benign lesions, the average lesion-to-liver SUVmax ratio was 2.5 ± 1.7 and the average lesion-to-blood-pool SUVmax ratio was 3.5 ± 2.4; there was no statistically significant difference between lesion-to-liver and lesion-to-blood-pool SUVmax ratios for benign and malignant lesions.
conclusionBecause PIU values are indicative of malignancy for a substantial percentage of patients, further investigation is required.
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