Evidence map›Paper›PMID 26153066›Full record

ArticlePsychopharmacology2015

Some of the people, some of the time: field evidence for associations and dissociations between stress and drug use.

Melody Furnari, David H Epstein, Karran A Phillips, Michelle L Jobes, William J Kowalczyk, Massoud Vahabzadeh, Jia-Ling Lin, Kenzie L Preston

Abstract read
PubMed Publisher
In one paragraph

Article in Psychopharmacology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 50 citations in OpenAlex.

  1. Stressor-elicited smoking and craving during a smoking cessation attempt.Journal of psychopathology and clinical science · 2022
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  17. Daily associations among craving, affect, and social interactions in the lives of patients during residential opioid use disorder treatment.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Melody FurnariClinical Pharmacology and Therapeutics Research Branch, Intramural Research Program, National Institute on Drug Abuse, Baltimore, MD, USA.
David H Epstein
Karran A Phillips
Michelle L Jobes
William J Kowalczyk
Massoud Vahabzadeh
Jia-Ling Lin
Kenzie L Preston
National Institute on Drug Abuse · US

Funding

Scientific Computing & Informatics Core (SCIC)ZIHDA000534 · NIDA · NATIONAL INSTITUTE ON DRUG ABUSE · PI ERIKSON, RYEN · 2009 to 2025
$65.3M
Real-Time Assessment of Drug Use, Along with Mental States and EnvironmentsZIADA000499 · NIDA · NATIONAL INSTITUTE ON DRUG ABUSE · PI EPSTEIN, DAVID · 2009 to 2025
$19.9M
Prevention of Relapse in AddictionZIADA000536 · NIDA · NATIONAL INSTITUTE ON DRUG ABUSE · PI PRESTON, KENZIE · 2009 to 2018
$9.5M
Intramural NIH HHS
6 · The paper itself

Abstract

rationaleStress's role in drug use is supported by retrospective interview and laboratory studies, but prospective data confirming the association in daily life are sparse.

objectivesThis study aims to assess the relationship between drug use and stress in real time with ambulatory monitoring.

methodsFor up to 16 weeks, 133 outpatients on opiate agonist treatment used smartphones to report each time they used drugs or felt more stressed than usual. They rated stress-event severity on a 10-point scale and as a hassle, day spoiler, or more than a day spoiler. For analysis, stress reports made within 72 h before a reported use of cocaine or opioid were binned into 24-h periods.

resultsOf 52 participants who reported stress events in the 72-h timeframe, 41 reported stress before cocaine use and 26 before opioid use. For cocaine use, the severity of stressors, rated numerically (r effect = 0.42, CL95 0.17-0.62, p = 0.00061) and percent rated as "more than a day spoiler" (r effect = 0.34, CL95 0.07-0.56, p = 0.0292)], increased linearly across the three days preceding use. The number of stressors did not predict cocaine use, and no measure of stress predicted opioid use. In ecological momentary assessment (EMA) from the whole sample of 133, stress and drug use occurred independently and there was no overall relationship.

conclusionsEMA did not support the idea that stress is a necessary or sufficient trigger for cocaine or heroin use after accounting for the base rates of stress and use. But EMA did show that stressful events can increase in severity in the days preceding cocaine use.

Indexed as

SmartphoneAdultCocaine-Related DisordersEmotionsFemaleHeroin DependenceHumansMaleMiddle AgedOpioid-Related DisordersProspective StudiesRetrospective StudiesStress, PsychologicalSubstance-Related DisordersTime Factors

Identifiers

PMID26153066
OpenAlexW783685611

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.