Evidence map›Paper›PMID 26152900›Full record

ArticleMagnetic resonance in medicine2016

Improved black-blood imaging using DANTE-SPACE for simultaneous carotid and intracranial vessel wall evaluation.

Yibin Xie, Qi Yang, Guoxi Xie, Jianing Pang, Zhaoyang Fan, Debiao Li

Registry-linked trialAbstract read
In one paragraph

Article in Magnetic resonance in medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05762367 (MR Lymphatic Imaging in Idiopathic Intracranial Hypertension), which is not on this map. Cited by 56 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05762367 nacompletednot on this mapstarted 2023, after this paper: background citation

MR Lymphatic Imaging in Idiopathic Intracranial Hypertension

TypeinterventionalSponsorInstitut National de la Santé Et de la Recherche Médicale, FranceRan2023 to 2025Enrolled40ConditionsIdiopathic Intracranial HypertensionArms3T MRI with Gadobutrol injection
3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Vessel Wall Imaging of Intracranial Arteries: Fundamentals and Clinical Applications.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2023
    Review
  12. Imaging of Intracranial Saccular Aneurysms.Stroke (Hoboken, N.J.) · 2023
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yibin XieBiomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Qi YangBiomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Guoxi XieBiomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Jianing PangBiomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Zhaoyang FanBiomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Debiao LiBiomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.

Funding

Flow Sensitive SSFP for Non-Contrast MRA and Vessel Wall ImagingR01HL096119 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI LI, DEBIAO · 2009 to 2018
$3.3M
NHLBI NIH HHS R01 HL096119
6 · The paper itself

Abstract

purposeThe purpose of this study was to develop a three-dimensional black blood imaging method for simultaneously evaluating the carotid and intracranial arterial vessel walls with high spatial resolution and excellent blood suppression with and without contrast enhancement.

methodsThe delay alternating with nutation for tailored excitation (DANTE) preparation module was incorporated into three-dimensional variable flip angle turbo spin echo (SPACE) sequence to improve blood signal suppression. Simulations and phantom studies were performed to quantify image contrast variations induced by DANTE. DANTE-SPACE, SPACE, and two-dimensional turbo spin echo were compared for apparent signal-to-noise ratio, contrast-to-noise ratio, and morphometric measurements in 14 healthy subjects. Preliminary clinical validation was performed in six symptomatic patients.

resultsApparent residual luminal blood was observed in five (pre-contrast) and nine (post-contrast) subjects with SPACE and only two (post-contrast) subjects with DANTE-SPACE. DANTE-SPACE showed 31% (pre-contrast) and 100% (post-contrast) improvement in wall-to-blood contrast-to-noise ratio over SPACE. Vessel wall area measured from SPACE was significantly larger than that from DANTE-SPACE due to possible residual blood signal contamination. DANTE-SPACE showed the potential to detect vessel wall dissection and identify plaque components in patients.

conclusionDANTE-SPACE significantly improved arterial and venous blood suppression compared with SPACE. Simultaneous high-resolution carotid and intracranial vessel wall imaging to potentially identify plaque components was feasible with a scan time under 6 min. Magn Reson Med 75:2286-2294, 2016. © 2015 Wiley Periodicals, Inc.

Indexed as

AdultCarotid ArteriesContrast MediaFemaleHumansImage Processing, Computer-AssistedMagnetic Resonance AngiographyMaleMiddle AgedReproducibility of ResultsSignal-To-Noise RatioStrokeYoung AdultContrast Mediablack-blood imagingcarotid artery imagingDANTEintracranial artery imagingSPACEvessel wall imaging

Identifiers

PMID26152900
PMCPMC4706507

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.