ArticleParasites & vectors2015
Exposure to Leishmania spp. and sand flies in domestic animals in northwestern Ethiopia.
Article in Parasites & vectors, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
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Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.
- Visceral leishmaniasis elimination in Ethiopia: insights into epidemiology, transmission, treatment access, and outcome - a systematic review and meta-analysis.BMC infectious diseases · 2026Pooled it
- Specificity of Phlebotomus papatasi and Phlebotomus tobbi recombinant salivary proteins developed as serological surveillance tool.Parasites & vectors · 2026Article
- Seroprevalence and associated factors of Leishmania infantum in small ruminants in Portugal.Parasites & vectors · 2026Article
- Seroprevalence ofTransboundary and emerging diseases · 2025Article
- Dogs as Reservoirs for Leishmania donovani, Bihar, India, 2018-2022.Emerging infectious diseases · 2024Article
- The complexities of blood-feeding patterns in mosquitoes and sandflies and the burden of disease: A minireview.Veterinary medicine and science · 2024Review
- First Evidence ofAnimals : an open access journal from MDPI · 2024Article
- Global Distribution of Canine Visceral Leishmaniasis and the Role of the Dog in the Epidemiology of the Disease.Pathogens (Basel, Switzerland) · 2024Review
- Infection ofTropical medicine and infectious disease · 2024Article
- Presence of anti-Leishmania infantum antibodies in sheep (Ovis aries) in Spain.Veterinary research communications · 2024Article
- Sex-structured disease transmission model and control mechanisms for visceral leishmaniasis (VL).PloS one · 2024Article
- Rodents as vehicle for delivery of transgenic bacteria to make paratransgenic sand fly vectors of cutaneous leishmaniasis in field condition.Scientific reports · 2023Article
- First report of Leishmania (Mundinia) martiniquensis in South American territory and confirmation of Leishbunyavirus infecting this parasite in a mare.Memorias do Instituto Oswaldo Cruz · 2023Article
- Making the Most of Its Short Reads: A Bioinformatics Workflow for Analysing the Short-Read-Only Data ofBiology · 2022Article
- Livestock infected with Leishmania spp. in southern Iran.Parasites & vectors · 2022Article
- Domestic mammals as reservoirs for Leishmania donovani on the Indian subcontinent: Possibility and consequences on elimination.Transboundary and emerging diseases · 2022Review
- Prevalence and risk factors of Toxoplasma gondii and Leishmania spp. infections in apparently healthy dogs in west Shewa zone, Oromia, Ethiopia.BMC veterinary research · 2021Article
- Opportunistic feeding behaviour and Leishmania infantum detection in Phlebotomus perniciosus females collected in the human leishmaniasis focus of Madrid, Spain (2012-2018).PLoS neglected tropical diseases · 2021Article
- Feeding behavior and activity of Phlebotomus pedifer and potential reservoir hosts of Leishmania aethiopica in southwestern Ethiopia.PLoS neglected tropical diseases · 2020Article
- Studies of host preferences of wild-caught Phlebotomus orientalis and Ph. papatasi vectors of leishmaniasis in Sudan.PloS one · 2020Article
Corrections and comments
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Authors and funding
15 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHuman visceral leishmaniasis caused by Leishmania donovani is considered an anthroponosis; however, Leishmania-infected animals have been increasingly reported in L. donovani foci, and the role of these animals as reservoirs for human L. donovani infection remains unclear.
methodsWe conducted a study of domestic animals (goats, sheep, cows, dogs, and donkeys) in three L. donovani foci in northwestern Ethiopia. Domestic animals were screened for Leishmania DNA and for anti-L. donovani IgG. Serum anti-sand fly saliva antibodies were used as a marker of exposure to the vector sand fly, Phlebotomus orientalis.
resultsOf 546 animals tested, 32 (5.9%) were positive for Leishmania DNA, with positive animals identified among all species studied. Sequencing indicated that the animals were infected with parasites of the L. donovani complex but could not distinguish between L. infantum and L. donovani. A total of 18.9% of the animals were seropositive for anti-L. donovani IgG, and 23.1% of the animals were seropositive for anti-P. orientalis saliva IgG, with the highest seroprevalence observed in dogs and sheep. A positive correlation was found between anti-P. orientalis saliva and anti-L. donovani IgGs in cows, goats, and sheep.
conclusionsThe detection of L. donovani complex DNA in the blood of domestic animals, the reported seroprevalence to the L. donovani antigen, and the widespread exposure to sand fly saliva among domestic animals indicate that they are frequently exposed to Leishmania infection and are likely to participate in the epidemiology of Leishmania infection, either as potential blood sources for sand flies or possibly as parasite hosts.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.