Evidence map›Paper›PMID 26151901›Full record

ArticleDevelopmental cell2015

NEGotiating Cell Identity through Regulated Cytoplasmic Polyadenylation.

Pradeep M Joshi, Joel H Rothman

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in Developmental cell, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 10 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Pradeep M JoshiDepartment of MCD Biology and Neuroscience Research Institute, University of California, Santa Barbara, Santa Barbara, CA 93106, USA.
Joel H RothmanDepartment of MCD Biology and Neuroscience Research Institute, University of California, Santa Barbara, Santa Barbara, CA 93106, USA; School of Biological Sciences, University of Auckland, Auckland 1010, New Zealand. Electronic address: joel.rothman@lifesci.ucsb.edu.
University of Auckland · NZUniversity of California, Santa Barbara · US

Funding

Developmental reprogramming and transorganogenesisR01HD081266 · NICHD · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI Joel H. Rothman · 2015 to 2026
$3.0M
Plasticity in an embryonic gene regulatory networkR01HD082347 · NICHD · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI ROTHMAN, JOEL H. · 2015 to 2019
$1.5M
NICHD NIH HHS R01 HD081266NICHD NIH HHS R01 HD082347
6 · The paper itself

Abstract

In this issue of Developmental Cell, Elewa et al. (2015) show that combinatorial action of RNA binding proteins modulates poly(A) tail length of maternal mRNAs, leading to asymmetric expression of a cell fate determinant in early C. elegans embryos. Genome-wide profiling suggests this mechanism may be widely used to establish cell identities.

Indexed as

AnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsCarrier ProteinsCytoplasmNuclear ProteinsPolyadenylationRNA, HelminthRNA, MessengerCaenorhabditis elegans ProteinsCarrier ProteinsNuclear ProteinsRNA, HelminthRNA, Messenger

Identifiers

PMID26151901
OpenAlexW1732967522

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.