ArticlePloS one2015
Changes in Cross-Sectional Area and Transverse Diameter of the Heart on Inspiratory and Expiratory Chest CT: Correlation with Changes in Lung Size and Influence on Cardiothoracic Ratio Measurement.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 25 citations in OpenAlex.
- Predictors of echocardiographic abnormalities in asymptomatic individuals with increased cardiothoracic ratio detected on chest radiography.American heart journal plus : cardiology research and practice · 2026Article
- Article
- Association between the Cardiothoracic Ratio on Chest X-rays and the Respiratory Function in Patients with Interstitial Lung Diseases: a Cross-sectional Study.Internal medicine (Tokyo, Japan) · 2025Article
- Adjustment of scan delay for bolus tracking with cardiothoracic ratio of CT scout image for hepatic artery phase of hepatic dynamic CT.Radiological physics and technology · 2024Article
- Chronic thromboembolic pulmonary hypertension is associated with a loss of total lung volume on computed tomography.World journal of radiology · 2023Article
- Radiological Cardiothoracic Ratio as a Potential Marker of Left Ventricular Hypertrophy Assessed by Echocardiography.Radiology research and practice · 2022Article
- Tailored stereotactic radiotherapy technique using deep inspiration breath-hold to reduce stomach dose for cardiac radioablation.Radiation oncology journal · 2021Article
- Radiological Cardiothoracic Ratio in Evidence-Based Medicine.Journal of clinical medicine · 2021Review
- Correlation between heart size and emphysema in patients with chronic obstructive pulmonary disease: CT-based analysis using inspiratory and expiratory scans.Chronic respiratory disease · 2018Article
- 3D-measurement of tracheobronchial angles on inspiratory and expiratory chest CT in COPD: respiratory changes and correlation with airflow limitation.International journal of chronic obstructive pulmonary disease · 2018Article
- Mediastinal pulmonary artery is associated with greater artery diameter and lingular division volume.Scientific reports · 2017Article
- Hyperinflated lungs compress the heart during expiration in COPD patients: a new finding on dynamic-ventilation computed tomography.International journal of chronic obstructive pulmonary disease · 2017Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe aim of this study was to investigate physiological changes in cardiac area and diameters between inspiratory and expiratory chest computed tomography (CT), and to assess their correlation with lung size change and influence on cardiothoracic ratio (CTR) measurements. MATERIALS AND
methodsThe institutional review board of our institution approved this study, and informed consent was waived. Forty-three subjects underwent inspiratory and expiratory chest CT as part of routine clinical care. On both inspiratory and expiratory scans, lung volumes and maximum lung diameters (transverse and vertical directions) were measured. The maximum cardiac cross-sectional area (CSA) and the maximum transverse cardiac diameter were measured on both scans, and the CT-based CTR was calculated. Changes in the lung and cardiac measurements were expressed as the expiratory/inspiratory (E/I) ratios. Comparisons between inspiratory and expiratory measurements were made by the Wilcoxon signed-rank test. Correlations between the E/I ratios of lung and heart measurements were evaluated by Spearman's rank correlation analysis.
resultsCardiac CSA and transverse cardiac diameter was significantly larger on expiratory than on inspiratory CT (p < 0.0001). Significant negative correlations were found between the E/I ratios of these cardiac measurements and the E/I ratios of lung volume and vertical lung diameter (p < 0.01). CT-based CTR was significantly larger on expiration than on inspiration (p < 0.0001).
conclusionsHeart size on chest CT depends on the phase of ventilation, and is correlated with changes in lung volume and craniocaudal lung diameter. The CTR is also significantly influenced by ventilation.
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