Evidence map›Paper›PMID 26150907›Full record

ReviewClinical and translational allergy2015

Innate lymphocyte cells in asthma phenotypes.

Leyla Pur Ozyigit, Hideaki Morita, Mubeccel Akdis

Erratum issuedOpen access · goldAbstract readReview
In one paragraph

Review in Clinical and translational allergy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Article
  3. Asthma Phenotypes in the Era of Personalized Medicine.Journal of clinical medicine · 2023
    Review
  4. Review
  5. Innate-like Lymphocytes and Innate Lymphoid Cells in Asthma.Clinical reviews in allergy & immunology · 2020
    Review
  6. Review
  7. Review
  8. Airway innate lymphoid cells in the induction and regulation of allergy.Allergology international : official journal of the Japanese Society of Allergology · 2019
    Review
  9. Article
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Leyla Pur OzyigitDepartment of Allergy and Immunology, Koç University, School of Medicine, Istanbul, Turkey.
Hideaki MoritaSwiss Institute of Allergy and Asthma Research, University of Zurich, Zurich, Switzerland ; Christine Kühne-Center for Allergy Research and Education, Davos, Switzerland.
Mubeccel AkdisSwiss Institute of Allergy and Asthma Research, University of Zurich, Zurich, Switzerland ; Christine Kühne-Center for Allergy Research and Education, Davos, Switzerland.
CK-CARE · CHKoç University · TRUniversity of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

T helper type 2 (TH2) cells were previously thought to be the main initiating effector cell type in asthma; however, exaggerated TH2 cell activities alone were insufficient to explain all aspects of asthma. Asthma is a heterogeneous syndrome comprising different phenotypes that are characterized by their different clinical features, treatment responses, and inflammation patterns. The most-studied subgroups of asthma include TH2-associated early-onset allergic asthma, late-onset persistent eosinophilic asthma, virus-induced asthma, obesity-related asthma, and neutrophilic asthma. The recent discovery of human innate lymphoid cells capable of rapidly producing large amounts of cytokines upon activation and the mouse data pointing to an essential role for these cells in asthma models have emphasized the important role of the innate immune system in asthma and have provided a new means of better understanding asthma mechanisms and differentiating its phenotypes.

Indexed as

AirwaysAsthmaCytokinesInnate immunityPhenotype

Identifiers

PMID26150907
PMCPMC4491887
OpenAlexW1845407473

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.