Evidence map›Paper›PMID 26150745›Full record

ArticleSaudi journal of biological sciences2015

Antibiotic resistance modulation by natural products obtained from Nasutitermes corniger (Motschulsky, 1855) and its nest.

Thiago P Chaves, Elaine L C Clementino, Delcio C Felismino, Rômulo R N Alves, Alexandre Vasconcellos, Henrique D M Coutinho, Ana Cláudia D Medeiros

Open access · hybridAbstract read
In one paragraph

Article in Saudi journal of biological sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Edible and medicinal termites: a global overview.Journal of ethnobiology and ethnomedicine · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Thiago P ChavesUniversidade Federal do Piauí, Campus Professora Cinobelina Elvas, Bom Jesus, PI 64900-000, Brazil ; Laboratório de Desenvolvimento e Ensaios de Medicamentos, Centro de Ciências Biológicas e da Saúde, Universidade Estadual da Paraíba, Campina Grande, Paraíba 58.429-500, Brazil.
Elaine L C ClementinoLaboratório de Desenvolvimento e Ensaios de Medicamentos, Centro de Ciências Biológicas e da Saúde, Universidade Estadual da Paraíba, Campina Grande, Paraíba 58.429-500, Brazil.
Delcio C FelisminoDepartamento de Biologia, Centro de Ciências Biológicas e da Saúde, Universidade Estadual da Paraíba, Campina Grande, Paraíba 58.429-500, Brazil.
Rômulo R N AlvesDepartamento de Biologia, Centro de Ciências Biológicas e da Saúde, Universidade Estadual da Paraíba, Campina Grande, Paraíba 58.429-500, Brazil.
Alexandre VasconcellosUniversidade Federal do Rio Grande do Norte, Departamento de Botânica, Ecologia e Zoologia, Natal, RN 59072-900, Brazil.
Henrique D M CoutinhoLaboratório de Microbiologia e Biologia Molecular, Universidade Regional do Cariri, Crato, CE 63105-000, Brazil.
Ana Cláudia D MedeirosLaboratório de Desenvolvimento e Ensaios de Medicamentos, Centro de Ciências Biológicas e da Saúde, Universidade Estadual da Paraíba, Campina Grande, Paraíba 58.429-500, Brazil.
Universidade Estadual da Paraíba · BRUniversidade Federal do Piauí · BRUniversidade Federal do Rio Grande do Norte · BRUniversidade Regional do Cariri · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Insects and their products are included in the traditional pharmacopoeia of various ethnic groups worldwide. In the Brazilian semiarid region can be highlighted the use of the termite Nasutitermes corniger for the treatment of various diseases. This study evaluated the ethanol extract of N. corniger and its nest as an antimicrobial agent and as a modulator of bacterial resistance against multidrug strains. The Minimum Inhibitory Concentration (MIC) of the extract on Staphylococcus aureus and Escherichia coli by microdilution was determined, as well as MIC of antibiotics in the presence and absence of extract. Despite having no significant antimicrobial activity (MIC ⩾ 1000 μg mL(-1)), the extract showed additive activity to the antibiotic efficacy, significantly reducing its MIC. These results suggest that N. corniger and its nest are promising natural products for use in antimicrobial therapy.

Indexed as

Antimicrobial activityEthnopharmacologyInsectModification of resistanceSynergistic effectZootherapy

Identifiers

PMID26150745
PMCPMC4486467
OpenAlexW2093640542

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.