ArticleInternational journal of chronic obstructive pulmonary disease2015
Peak expiratory flow rate as a surrogate for forced expiratory volume in 1 second in COPD severity classification in Thailand.
Article in International journal of chronic obstructive pulmonary disease, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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12 citing papers in PubMed, 28 citations in OpenAlex.
- SLC26A9 SNP rs7512462 is not associated with lung disease severity or lung function response to ivacaftor in cystic fibrosis patients with G551D-CFTR.Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society · 2021Observational
- COPD & COVID-19.Archivos de bronconeumologia · 2021Article
- COPD & COVID-19.Archivos de bronconeumologia · 2021Article
- Peak expiratory flow rate and sarcopenia risk in older Indonesian people: A nationwide survey.PloS one · 2021Article
- Global Initiative for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease. The 2020 GOLD Science Committee Report on COVID-19 and Chronic Obstructive Pulmonary Disease.American journal of respiratory and critical care medicine · 2021Review
- Review
- Screening asymptomatic school children for early asthma by determining airway narrowing through peak expiratory flow rate measurement.Journal of education and health promotion · 2020Article
- Joint Indian Chest Society-National College of Chest Physicians (India) guidelines for spirometry.Lung India : official organ of Indian Chest Society · 2019Article
- Comparison between Emergency Severity Index plus peak flow meter and Emergency Severity Index in the dyspneic patients with chronic obstructive pulmonary disease: A randomized clinical trial.Turkish journal of emergency medicine · 2019Article
- Personality and Lung Function in Older Adults.The journals of gerontology. Series B, Psychological sciences and social sciences · 2017Article
- Nebulised magnesium sulphate as an adjuvant to the treatment of acute exacerbation of COPD: A systematic review and meta-analysis of randomised controlled trials with trial sequential analysis.Lung India : official organ of Indian Chest SocietyArticle
- Agreement between forced expiratory volume in the first second (FEVLung India : official organ of Indian Chest SocietyArticle
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere are limited studies directly comparing correlation and agreement between peak expiratory flow rate (PEFR) and forced expiratory volume in 1 second (FEV1) for severity classification of COPD. However, clarifying the role of PEFR as a surrogate of COPD severity classification instead of FEV1 is essential in situations and areas where spirometry is not routinely available. PURPOSE: To evaluate the agreement between FEV1 and PEFR using Global initiative for chronic Obstructive Lung Disease (GOLD) severity classification criteria. MATERIALS AND
methodsThis cross-sectional study included stable COPD patients. Both absolute values and % predicted FEV1 and % predicted PEFR were obtained from the same patients at a single visit. The severity of COPD was classified according to GOLD criteria. Pearson's correlation coefficient was used to examine the relationship between FEV1 and PEFR. The agreement of % predicted FEV1 and % predicted PEFR in assigning severity categories was calculated using Kappa statistic, and identification of the limits of agreement was by Bland-Altman analysis. Statistical significance was set at P-value <0.05.
resultsThree hundred stable COPD patients were enrolled; 195 (65.0%) male, mean age 70.4±9.4 years, and mean % predicted FEV1 51.4±20.1. Both correlations between the % predicted FEV1 and PEFR as well as the absolute values were strongly significant (r=0.76, P<0.001 and r=0.87, P<0.001, respectively). However, severity categories of airflow limitation based on % predicted FEV1 or PEFR intervals were concordant in only 179 patients (59.7%). The Kappa statistic for agreement was 0.41 (95% confidence interval, 0.34-0.48), suggesting unsatisfied agreement. The calculated limits of agreement were wide (+27.1% to -28.9%).
conclusionAlthough the correlation between FEV1 and PEFR measurements were strongly significant, the agreement between the two tests was unsatisfied and may influence inappropriate clinical decision making in diagnosis, severity classification, and management of COPD.
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