Evidence map›Paper›PMID 26150708›Full record

Observational studyClinical interventions in aging2015

Geriatrician interventions on medication prescribing for frail older people in residential aged care facilities.

Arjun Poudel, Nancye M Peel, Charles A Mitchell, Leonard C Gray, Lisa M Nissen, Ruth E Hubbard

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Clinical interventions in aging, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 4 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 4 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Arjun PoudelSchool of Pharmacy, The University of Queensland, Brisbane, QLD, Australia.
Nancye M PeelCentre for Research in Geriatric Medicine, The University of Queensland, Brisbane, QLD, Australia.
Charles A MitchellSchool of Pharmacy, The University of Queensland, Brisbane, QLD, Australia.
Leonard C GrayCentre for Research in Geriatric Medicine, The University of Queensland, Brisbane, QLD, Australia.
Lisa M NissenSchool of Pharmacy, The University of Queensland, Brisbane, QLD, Australia ; School of Clinical Sciences, Queensland University of Technology, Brisbane, QLD, Australia.
Ruth E HubbardCentre for Research in Geriatric Medicine, The University of Queensland, Brisbane, QLD, Australia.
University of Queensland · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveIn Australian residential aged care facilities (RACFs), the use of certain classes of high-risk medication such as antipsychotics, potent analgesics, and sedatives is high. Here, we examined the prescribed medications and subsequent changes recommended by geriatricians during comprehensive geriatric consultations provided to residents of RACFs via videoconference.

designThis is a prospective observational study.

settingFour RACFs in Queensland, Australia, are included.

participantsA total of 153 residents referred by general practitioners for comprehensive assessment by geriatricians delivered by video-consultation.

resultsResidents' mean (standard deviation, SD) age was 83.0 (8.1) years and 64.1% were female. They had multiple comorbidities (mean 6), high levels of dependency, and were prescribed a mean (SD) of 9.6 (4.2) regular medications. Ninety-one percent of patients were taking five or more medications daily. Of total medications prescribed (n=1,469), geriatricians recommended withdrawal of 9.8% (n=145) and dose alteration of 3.5% (n=51). New medications were initiated in 47.7% (n=73) patients. Of the 10.3% (n=151) medications considered as high risk, 17.2% were stopped and dose altered in 2.6%.

conclusionThere was a moderate prevalence of potentially inappropriate high-risk medications. However, geriatricians made relatively few changes, suggesting either that, on balance, prescription of these medications was appropriate or, because of other factors, there was a reluctance to adjust medications. A structured medication review using an algorithm for withdrawing medications of high disutility might help optimize medications in frail patients. Further research, including a broader survey, is required to understand these dynamics.

Indexed as

Frail ElderlyHomes for the AgedNursing HomesAgedAged, 80 and overAustraliaComorbidityFemaleGeriatric AssessmentGeriatricsHumansMaleMedication Therapy ManagementPolypharmacyProspective Studiesfrail oldergeriatrician interventionhigh-risk medicationsresidential aged care facilities

Identifiers

PMID26150708
PMCPMC4485794
OpenAlexW1768664898

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.