ArticlePatient preference and adherence2015
Reasons for not initiating osteoporosis therapy among a managed care population.
Article in Patient preference and adherence, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- Determinants, consequences and potential solutions to poor adherence to anti-osteoporosis treatment: results of an expert group meeting organized by the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) and the International Osteoporosis Foundation (IOF).Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2019Pooled it
- Reasons for Primary Medication Nonadherence: A Systematic Review and Metric Analysis.Journal of managed care & specialty pharmacy · 2018Pooled it
- Evaluation of a Multimodal, Direct-to-Patient Educational Intervention Targeting Barriers to Osteoporosis Care: A Randomized Clinical Trial.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2018Trial
- Implementation of a Web-Based Application (Wellhealth) for Osteoporosis Medication Management in Older Adults: Prospective Feasibility Study.JMIR formative research · 2026Article
- Assessing endocrinology referral rates and osteoporosis directed-care after upper extremity fragility fractures.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025Article
- Study on differentially expressed genes and pattern recognition receptors in osteoporosis based on bioinformatics analysis.Scientific reports · 2025Article
- Improving patients' experiences of diagnosis and treatment of vertebral fracture: co-production of knowledge sharing resources.BMC musculoskeletal disorders · 2024Article
- Fragility fracture care gap at a tertiary teaching hospital in Malaysia.Archives of osteoporosis · 2023Article
- Characteristics of subsequent contralateral proximal femoral fracture: more convenient access is needed to treat osteoporosis.Journal of orthopaedic surgery and research · 2023Article
- Exploring the osteoporosis treatment gap after fragility hip fracture at a Tertiary University Medical Center in Thailand.BMC geriatrics · 2023Article
- Patients not taking a previously prescribed bone active medication now prescribed medication through Ontario FLS.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2022Article
- Challenges in osteoporosis treatment initiation in geriatric patients admitted under the hip-fracture pathway.Archives of osteoporosis · 2022Article
- The clinician's guide to prevention and treatment of osteoporosis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2022Article
- Protocol for the models of primary osteoporosis screening in men (MOPS) cluster randomized trial.Contemporary clinical trials · 2022Article
- Use of path modeling to inform a clinical decision support application to encourage osteoporosis medication use.Research in social & administrative pharmacy : RSAP · 2021Article
- Factors associated with the contemplative stage of readiness to initiate osteoporosis treatment.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2020Article
- Article
- Influence of bone densitometry on the anti-osteoporosis treatment after fragility hip fracture.Aging clinical and experimental research · 2019Article
- Osteoporosis prevention: where are the barriers to improvement in a French general population? A qualitative study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2019Article
- Factors related to intentional non-initiation of bisphosphonate treatment in patients with a high fracture risk in primary care: a qualitative study.BMC family practice · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMany women with osteoporosis do not initiate osteoporosis treatment.
objectiveTo examine patients' reasons for not initiating osteoporosis treatment among women with osteoporosis.
methodsSurvey recipients were identified from a national US claims database and included women ≥55 years with an osteoporosis diagnosis from January 1, 2010 to March 31, 2012 as defined by: 1) osteoporosis diagnosis coupled with bone mineral density test within 183 days of diagnosis and/or 2) osteoporosis-related fracture. Eligibility required no claims for osteoporosis medication 1) at least 12 months and up to 5 years prior to osteoporosis diagnosis and 2) at least 6 months after osteoporosis diagnosis. Continuous enrollment for 18 months (6 months pre-osteoporosis and 12 months post-osteoporosis diagnosis) was also required. A total of 2,000 patients with the most recent osteoporosis diagnosis were mailed a survey. Respondents reporting that they did not initiate physician-recommended osteoporosis medication, after either their physician told them they had osteoporosis or they experienced a fracture since age 45 years, were asked for reasons why they did not initiate treatment.
resultsThere were 430 patients who returned a complete survey; mean age was 61% and 21.6% had a fracture. A total of 197 (45.8%) patients reported their physician diagnosed osteoporosis and 117 (59.3%) of those were recommended osteoporosis medication; 44 of the 117 patients (37.6%) did not initiate recommended osteoporosis medication by the time of survey. The primary reasons for not initiating osteoporosis medication were concern over side effects (77.3%), medication costs (34.1%), and pre-existing gastrointestinal concerns (25.0%).
conclusionAmong respondents, 41% of patients whose physician diagnosed osteoporosis were not recommended osteoporosis treatment and 38% of patients who were recommended osteoporosis treatment did not initiate treatment within approximately 2 years of diagnosis. Concerns with side effects of osteoporosis treatment, medication costs, and pre-existing gastrointestinal concerns were the most common reasons for not initiating recommended treatment.
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