ArticleApplied and environmental microbiology2015
Variation in the Microbiota of Ixodes Ticks with Regard to Geography, Species, and Sex.
Article in Applied and environmental microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 131 papers, 1 of them a synthesis that pooled it.
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Who cites it
131 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prevalence of Tick Infection with Bartonella in China: A Review and Meta-analysis.Acta parasitologica · 2024Pooled it
- Geographic Variation in the Bacterial Microbiota ofBiology · 2026Article
- Pilot metaproteomic profiling reveals bacterial diversity and potential medical and veterinary relevance of tick microbiomes in northern Algeria.Scientific reports · 2026Article
- Tick Microbiome and Its Role in Emerging Zoonotic Diseases and Transmissibility.Microorganisms · 2026Review
- Metagenomic surveillance of tick-borne pathogens and microbiomes in Huntingdon County, Pennsylvania.One health (Amsterdam, Netherlands) · 2026Article
- Ecological Frameworks of Pathogen-Pathogen and Pathogen-Microbiome Interactions Within the Tick Holobiont.Pathogens (Basel, Switzerland) · 2026Review
- Characterization of bacterial microbiome and molecular detection of rickettsiosis in free-living ticks (Amblyomma sculptum Berlese, 1888).Scientific reports · 2026Article
- Article
- Seasonal variation in the bacterial microbiome of questing nymphal ticks in Missouri, United States.Frontiers in microbiology · 2026Article
- Sexual and regional differences in the microbiome and functional metagenome of the lone star tick, Amblyomma americanum.Animal microbiome · 2025Article
- Geographic variation in the microbiome of Varroa destructor in the neighbouring countries Slovakia and Czechia.International microbiology : the official journal of the Spanish Society for Microbiology · 2025Article
- Infection-Mediated Shifts in the Microbial Communities of Deer-FedMicroorganisms · 2025Article
- Metagenomic Profile of Bacterial Communities ofPathogens (Basel, Switzerland) · 2025Article
- Diversity of the Ixodes ricinus Microbiome Across Belgian Ecoregions and Its Association with Pathogen and Symbiont Presence.Microbial ecology · 2025Article
- Host-Specificity and Network Structure of Tick Microbiota in Co-Distributed Species From the Iberian Peninsula.Ecology and evolution · 2025Article
- The bacterial diversity and potential pathogenic risks of giant panda-infesting ticks.Microbiology spectrum · 2025Article
- The Microbiome and Coxiella Diversity Found in Amblyomma hebraeum and Dermacentor rhinocerinus Ticks Sampled from White Rhinoceros.Microbial ecology · 2025Article
- A review of filarial nematodes parasitizing tick vectors: unraveling global patterns in species diversity, host associations, and interactions with tick-borne pathogens.Parasites & vectors · 2025Review
- Genomic and Proteomic Analyses of Bacterial Communities ofMicroorganisms · 2025Article
- Differential impact of spotted fever groupFrontiers in microbiology · 2025Article
71 more citing papers are in PubMed but not listed here.
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Authors and funding
17 authors.
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Abstract
Ixodes scapularis is the principal vector of Lyme disease on the East Coast and in the upper Midwest regions of the United States, yet the tick is also present in the Southeast, where Lyme disease is absent or rare. A closely related species, I. affinis, also carries the pathogen in the South but does not seem to transmit it to humans. In order to better understand the geographic diversity of the tick, we analyzed the microbiota of 104 adult I. scapularis and 13 adult I. affinis ticks captured in 19 locations in South Carolina, North Carolina, Virginia, Connecticut, and New York. Initially, ticks from 4 sites were analyzed by 454 pyrosequencing. Subsequently, ticks from these sites plus 15 others were analyzed by sequencing with an Illumina MiSeq machine. By both analyses, the microbiomes of female ticks were significantly less diverse than those of male ticks. The dissimilarity between tick microbiomes increased with distance between sites, and the state in which a tick was collected could be inferred from its microbiota. The genus Rickettsia was prominent in all locations. Borrelia was also present in most locations and was present at especially high levels in one site in western Virginia. In contrast, members of the family Enterobacteriaceae were very common in North Carolina I. scapularis ticks but uncommon in I. scapularis ticks from other sites and in North Carolina I. affinis ticks. These data suggest substantial variations in the Ixodes microbiota in association with geography, species, and sex.
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