Evidence map›Paper›PMID 26150344›Full record

ReviewAdvanced drug delivery reviews2016

Bioengineering methods for myocardial regeneration.

Hesam Parsa, Kacey Ronaldson, Gordana Vunjak-Novakovic

Abstract readReview
In one paragraph

Review in Advanced drug delivery reviews, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Genome Editing and Cardiac Regeneration.Advances in experimental medicine and biology · 2023
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Bioreactor Platform for Biomimetic Culture andFrontiers in bioengineering and biotechnology · 2020
    Article
  14. Article
  15. Cells, Materials, and Fabrication Processes for Cardiac Tissue Engineering.Frontiers in bioengineering and biotechnology · 2020
    Review
  16. Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hesam ParsaDepartment of Biomedical Engineering, Columbia University, New York, NY, United States.
Kacey RonaldsonDepartment of Biomedical Engineering, Columbia University, New York, NY, United States.
Gordana Vunjak-NovakovicDepartment of Biomedical Engineering, Columbia University, New York, NY, United States; Department of Medicine, Columbia University, New York, NY, United States. Electronic address: gv2131@columbia.edu.

Funding

Translational Bioreactors - Engineering Complex TissuesP41EB002520 · NIBIB · TUFTS UNIVERSITY MEDFORD · PI KAPLAN, DAVID L. · 2004 to 2018
$16.7M
Engineering Vascularized Cardiac MuscleR01HL076485 · NHLBI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Gordana Vunjak-Novakovic · 2005 to 2026
$9.2M
Tissue Chips for Rare Disease: Adding Timothy Syndrome to the HeLIVaSkCa platformUH3EB017103 · NIBIB · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI VUNJAK-NOVAKOVIC, GORDANA · 2014 to 2016
$7.1M
Training in Cardiovascular Translational ResearchT32HL120826 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MARKS, ANDREW ROBERT, TABAS, IRA A · 2014 to 2023
$4.7M
Integrated heart-liver-vascular systems for drug testing in human health and diseUH2EB017103 · NIBIB · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI VUNJAK-NOVAKOVIC, GORDANA · 2012 to 2013
$1.7M
NHLBI NIH HHS HL076485NHLBI NIH HHS R01 HL076485NHLBI NIH HHS T32 HL120826NIBIB NIH HHS EB002520NIBIB NIH HHS EB 17103NIBIB NIH HHS P41 EB002520NIBIB NIH HHS UH2 EB017103NIBIB NIH HHS UH3 EB017103
6 · The paper itself

Abstract

The challenging task of heart regeneration is being pursued in three related directions: derivation of cardiomyocytes from human stem cells, in vitro engineering and maturation of cardiac tissues, and development of methods for controllable cell delivery into the heart. In this review, we focus on tissue engineering methods that recapitulate biophysical signaling found during normal heart development and maturation. We discuss the use of scaffold-bioreactor systems for engineering functional human cardiac tissues, and the methods for delivering stem cells, cardiomyocytes and engineered tissues into the heart.

Indexed as

Tissue ScaffoldsAnimalsBiomechanical PhenomenaBiophysical PhenomenaBioreactorsCell DifferentiationElectrophysiological PhenomenaHeartHumansInduced Pluripotent Stem CellsMyocytes, CardiacRegenerationTissue EngineeringBioreactorCardiomyocyteCell and tissue delivery to the heartElectro-mechanical stimulationHuman induced pluripotent stem cellsTissue engineering

Identifiers

PMID26150344
PMCPMC4698189

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.