ArticlePlant biotechnology journal2016
Change of function of the wheat stress-responsive transcriptional repressor TaRAP2.1L by repressor motif modification.
Article in Plant biotechnology journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 62 citations in OpenAlex.
- Molecular and Physiological Responses of Plants that Enhance Cold Tolerance.International journal of molecular sciences · 2025Review
- Functional analysis of PagERF021 gene in salt stress tolerance in Populus alba × P. glandulosa.The plant genome · 2024Article
- Characterization of DREB family genes in Lotus japonicus and LjDREB2B overexpression increased drought tolerance in transgenic Arabidopsis.BMC plant biology · 2024Article
- Understanding role of roots in plant response to drought: Way forward to climate-resilient crops.The plant genome · 2024Review
- Evolution of the DEHYDRATION-RESPONSIVE ELEMENT-BINDING PROTEIN subfamily in green plants.Plant physiology · 2022Article
- Comprehensive genomic survey, structural classification and expression analysis of CBMC plant biology · 2021Article
- Elevation of GhDREB1B transcription by a copy number variant significantly improves chilling tolerance in cotton.Planta · 2021Article
- Plant Transcription Factors Involved in Drought and Associated Stresses.International journal of molecular sciences · 2021Review
- Impact of the overexpression of the StDREB1 transcription factor on growth parameters, yields, and chemical composition of tubers from greenhouse and field grown potato plants.Journal of plant research · 2021Article
- Article
- DREB/CBF expression in wheat and barley using the stress-inducible promoters of HD-Zip I genes: impact on plant development, stress tolerance and yield.Plant biotechnology journal · 2020Article
- Development of Drought-Tolerant Transgenic Wheat: Achievements and Limitations.International journal of molecular sciences · 2019Review
- Analysis of Rice Proteins with DLN Repressor Motif/S.International journal of molecular sciences · 2019Article
- The wheat TabZIP2 transcription factor is activated by the nutrient starvation-responsive SnRK3/CIPK protein kinase.Plant molecular biology · 2018Article
- The impact of drought on wheat leaf cuticle properties.BMC plant biology · 2017Article
- Wheat drought-responsive WXPL transcription factors regulate cuticle biosynthesis genes.Plant molecular biology · 2017Article
- Stress-responsive gene RsICE1 from Raphanus sativus increases cold tolerance in rice.Protoplasma · 2017Article
- Drought Response in Wheat: Key Genes and Regulatory Mechanisms Controlling Root System Architecture and Transpiration Efficiency.Frontiers in chemistry · 2017Review
- Identification and characterization of wheat drought-responsive MYB transcription factors involved in the regulation of cuticle biosynthesis.Journal of experimental botany · 2016Article
- The Banana Transcriptional Repressor MaDEAR1 Negatively Regulates Cell Wall-Modifying Genes Involved in Fruit Ripening.Frontiers in plant science · 2016Article
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13 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plants respond to abiotic stresses by changes in gene regulation, including stress-inducible expression of transcriptional activators and repressors. One of the best characterized families of drought-related transcription factors are dehydration-responsive element binding (DREB) proteins, known as C-repeat binding factors (CBF). The wheat DREB/CBF gene TaRAP2.1L was isolated from drought-affected tissues using a dehydration-responsive element (DRE) as bait in a yeast one-hybrid screen. TaRAP2.1L is induced by elevated abscisic acid, drought and cold. A C-terminal ethylene responsive factor-associated amphiphilic repression (EAR) motif, known to be responsible for active repression of target genes, was identified in the TaRAP2.1L protein. It was found that TaRAP2.1L has a unique selectivity of DNA-binding, which differs from that of DREB activators. This binding selectivity remains unchanged in a TaRAP2.1L variant with an inactivated EAR motif (TaRAP2.1Lmut). To study the role of the TaRAP2.1L repressor activity associated with the EAR motif in planta, transgenic wheat overexpressing native or mutated TaRAP2.1L was generated. Overexpression of TaRAP2.1L under constitutive and stress-inducible promoters in transgenic wheat and barley led to dwarfism and decreased frost tolerance. By contrast, constitutive overexpression of the TaRAP2.1Lmut gene had little or no negative influence on wheat development or grain yield. Transgenic lines with the TaRAP2.1Lmut transgene had an enhanced ability to survive frost and drought. The improved stress tolerance is attributed to up-regulation of several stress-related genes known to be downstream genes of DREB/CBF activators.
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