ArticleMicrobial cell factories2015
Inhibition of pathogenic and spoilage bacteria by a novel biofilm-forming Lactobacillus isolate: a potential host for the expression of heterologous proteins.
Article in Microbial cell factories, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Complete Genome Sequence Analysis and Probiotic Characterisation ofMicroorganisms · 2025Article
- Composite Probiotics Improve Gut Health and Enhance Tryptophan Metabolism in Nursery Piglets During Liquid Feeding.International journal of molecular sciences · 2025Article
- Pharmacological strategies for targeting biofilms in otorhinolaryngologic infections and overcoming antimicrobial resistance (Review).Biomedical reports · 2025Review
- Genome mining of Lactiplantibacillus plantarum PA21: insights into its antimicrobial potential.BMC genomics · 2024Article
- Immunomodulatory Activity on Human Macrophages by Cell-Free Supernatants to Explore the Probiotic and Postbiotic Potential of Lactiplantibacillus plantarum Strains of Plant Origin.Probiotics and antimicrobial proteins · 2024Article
- Lactic acid bacteria biofilms and their antimicrobial potential against pathogenic microorganisms.Biofilm · 2023Review
- Lactobacilli displacement and Candida albicans inhibition on initial adhesion assays: a probiotic analysis.BMC research notes · 2022Article
- Nutritional Content Dynamics and Correlation of Bacterial Communities and Metabolites in Fermented Pickled Radishes Supplemented With Wheat Bran.Frontiers in nutrition · 2022Article
- Formation and Transfer of Multi-Species Biofilms ContainingFrontiers in microbiology · 2022Article
- Using Lactobacilli to FightAntibiotics (Basel, Switzerland) · 2021Article
- Applications of Lactic Acid Bacteria and Their Bacteriocins against Food Spoilage Microorganisms and Foodborne Pathogens.Molecules (Basel, Switzerland) · 2021Review
- Isolation, identification and characterization ofHeliyon · 2021Article
- Effect ofAntibiotics (Basel, Switzerland) · 2021Article
- Insight into probiotic properties of lactic acid bacterial endosymbionts ofSaudi journal of biological sciences · 2021Article
- The impact of Lactobacillus on group B streptococcal interactions with cells of the extraplacental membranes.Microbial pathogenesis · 2020Article
- Comparative Study of Extracellular Proteolytic, Cellulolytic, and Hemicellulolytic Enzyme Activities and Biotransformation of Palm Kernel Cake Biomass by Lactic Acid Bacteria Isolated from Malaysian Foods.International journal of molecular sciences · 2019Article
- Chemical Transfers Occurring ThroughFrontiers in nutrition · 2019Article
- Efficacy of Using Probiotics with Antagonistic Activity against Pathogens of Wound Infections: An Integrative Review of Literature.BioMed research international · 2019Review
- The Inhibition Effect of Lactobacilli Against Growth and Biofilm Formation of Pseudomonas aeruginosa.Probiotics and antimicrobial proteins · 2018Article
- Effects of cell-free supernatant ofVeterinary research forum : an international quarterly journal · 2018Article
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBacterial biofilms are a preferred mode of growth for many types of microorganisms in their natural environments. The ability of pathogens to integrate within a biofilm is pivotal to their survival. The possibility of biofilm formation in Lactobacillus communities is also important in various industrial and medical settings. Lactobacilli can eliminate the colonization of different pathogenic microorganisms. Alternatively, new opportunities are now arising with the rapidly expanding potential of lactic acid bacteria biofilms as bio-control agents against food-borne pathogens.
resultsA new isolate Lactobacillus plantarum PA21 could form a strong biofilm in pure culture and in combination with several pathogenic and food-spoilage bacteria such as Salmonella enterica, Bacillus cereus, Pseudomonas fluorescens, and Aeromonas hydrophila. Exposure to Lb. plantarum PA21 significantly reduced the number of P. fluorescens, A. hydrophila and B. cereus cells in the biofilm over 2-, 4- and 6-day time periods. However, despite the reduction in S. enterica cells, this pathogen showed greater resistance in the presence of PA21 developed biofilm, either in the planktonic or biofilm phase. Lb. plantarum PA21 was also found to be able to constitutively express GFP when transformed with the expression vector pMG36e which harbors the gfp gene as a reporter demonstrating that the newly isolated strain can be used as host for genetic engineering.
conclusionIn this study, we evaluate the ability of a new Lactobacillus isolate to form strong biofilm, which would provide the inhibitory effect against several spoilage and pathogenic bacteria. This new isolate has the potential to serve as a safe and effective cell factory for recombinant proteins.
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