Evidence map›Paper›PMID 26149834›Full record

ArticleThe British journal of dermatology2015

Identification of translational dermatology research priorities in the U.K.: results of an electronic Delphi exercise.

E Healy, S J Brown, S M Langan, S G Nicholls, K Shams, N J Reynolds

Open access · greenAbstract read
In one paragraph

Article in The British journal of dermatology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Understanding Patient Priorities for Psoriatic Disease Research.Journal of psoriasis and psoriatic arthritis · 2025
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  10. Translating translation into patient benefit for atopic eczema.The British journal of dermatology · 2016
    Review
  11. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

E HealyDermatopharmacology, Sir Henry Wellcome Laboratories, Faculty of Medicine, University of Southampton, Southampton, UK.
S J Brown *Department of Dermatology, Ninewells Hospital & Medical School, Dundee, UK.
S M Langan *Faculty of Epidemiology and Population Health, London School of Tropical Medicine, London, UK.
S G Nicholls *Department of Epidemiology and Community Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Canada.
K Shams *Chemokine Research Group, Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
N J ReynoldsDermatology, Institute of Cellular Medicine, Medical School, Newcastle University, Newcastle upon Tyne, UK.
Southampton General Hospital · GBUniversity of Ottawa · CA

Funding

CIHR 122403Department of Health NIHR/CS/010/014Wellcome Trust 086398Wellcome Trust 100119Wellcome Trust WT086398MAWellcome Trust WT100119/Z/12/Z
6 · The paper itself

Abstract

backgroundTranslational research is the direct application of basic and applied research to patient care. It is estimated that there are at least 2000 different skin diseases; thus, there are considerable challenges in seeking to undertake research on each of these disorders.

objectivesThis electronic Delphi (e-Delphi) exercise was conducted in order to generate a list of translational dermatology research questions that are regarded as a priority for further investigations.

methodsDuring the first phase of the e-Delphi exercise, 228 research questions were generated by an expert panel that included clinical academic dermatologists, clinical dermatologists, nonclinical scientists, dermatology trainees and representatives from patient support groups.

resultsFollowing completion of the second and third phases, 40 questions on inflammatory skin disease, 20 questions on structural skin disorders/genodermatoses, 37 questions on skin cancer and eight miscellaneous questions were designated as priority translational dermatology research questions (PRQs). In addition to PRQs on a variety of disease areas (including multiple PRQs on psoriasis, eczema, squamous cell carcinoma and melanoma), there were a number of cross-cutting themes that identified a need to investigate mechanisms/pathogenesis of disease and the necessity to improve treatments for patients with skin disease.

conclusionsIt is predicted that this list of PRQs will help to provide a strategic direction for translational dermatology research in the U.K. and that addressing this list of questions will ultimately provide clinical benefit for substantial numbers of patients with skin disorders.

Indexed as

DermatologyResearchDelphi TechniqueHumansInternetSkin DiseasesTranslational Research, BiomedicalUnited Kingdom

Identifiers

PMID26149834
PMCPMC5038882
OpenAlexW2103801406

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.