Evidence map›Paper›PMID 26149464›Full record

ArticleAdvanced healthcare materials2015

Biotunable acoustic node assembly of organoids.

Pu Chen, Sinan Güven, Osman Berk Usta, Martin L Yarmush, Utkan Demirci

Abstract read
In one paragraph

Article in Advanced healthcare materials, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed.

  1. Article
  2. Article
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  4. Article
  5. Review
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  8. Article
  9. Acoustic Cell Patterning for Structured Cell-Laden Hydrogel Fibers/Tubules.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  10. Engineering Heterogeneous Tumor Models for Biomedical Applications.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Review
  11. FastSkinJournal of clinical medicine · 2023
    Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Review
  17. Article
  18. Review
  19. Review
  20. Cardiac Organoids and Gastruloids to Study Physio-Pathological Heart Development.Journal of cardiovascular development and disease · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Pu ChenBio-Acoustic MEMS in Medicine (BAMM) Lab, Canary Center at Stanford for Early Cancer Detection, Department of Radiology, School of Medicine, Stanford University, Palo Alto, CA, 94304, USA.
Sinan GüvenBio-Acoustic MEMS in Medicine (BAMM) Lab, Canary Center at Stanford for Early Cancer Detection, Department of Radiology, School of Medicine, Stanford University, Palo Alto, CA, 94304, USA.
Osman Berk UstaCenter for Engineering in Medicine at Massachusetts General Hospital, Harvard Medical School and Shriners Hospital for Children, 51 Blossom St., Boston, MA, 02114, USA.
Martin L YarmushCenter for Engineering in Medicine at Massachusetts General Hospital, Harvard Medical School and Shriners Hospital for Children, 51 Blossom St., Boston, MA, 02114, USA.
Utkan DemirciBio-Acoustic MEMS in Medicine (BAMM) Lab, Canary Center at Stanford for Early Cancer Detection, Department of Radiology, School of Medicine, Stanford University, Palo Alto, CA, 94304, USA.

Funding

Bio-MicroElectroMechanical Systems Resource CenterP41EB002503 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI TONER, MEHMET · 2004 to 2018
$17.4M
VECTOR COREP30NS069375 · NINDS · STANFORD UNIVERSITY · PI STEINBERG, GARY K · 2011 to 2019
$6.3M
Measuring the Temporal-Spatial Responses of Dormancy and Drug Resistance in a Human Breast Cancer Metastatic Niche within a Liver-on-a-Chip Microphysiological PlatformUH3TR000503 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI TAYLOR, D. LANSING · 2014 to 2016
$6.2M
Minimizing the role of cryoprotectant toxicity for cryopreservationR01EB015776 · NIBIB · STANFORD UNIVERSITY · PI DEMIRCI, UTKAN · 2012 to 2015
$1.5M
Magnetic Cellular Assembly and Microfluidic Conditioning for Generation of FunctiR15HL115556 · NHLBI · UNIVERSITY OF LOUISVILLE · PI GIRIDHARAN, GURUPRASAD A · 2013 to 2013
$476k
Nano-Acoustic Masonry of Microgels for Bottom-Up Tissue EngineeringR21HL112114 · NHLBI · PENNSYLVANIA STATE UNIVERSITY, THE · PI DEMIRCI, UTKAN, DEMIREL, MELIK · 2012 to 2013
$452k
NCATS NIH HHS 4UH3TR000503-03NCATS NIH HHS UH3 TR000503NHLBI NIH HHS R15 HL115556NHLBI NIH HHS R15HL115556NHLBI NIH HHS R21 HL112114NHLBI NIH HHS R21-HL112114NIBIB NIH HHS 1R01EB015776NIBIB NIH HHS 2P41EB002503-11NIBIB NIH HHS P41 EB002503NIBIB NIH HHS R01 EB015776NINDS NIH HHS NS069375
6 · The paper itself

Abstract

Bioengineering of 3D microtissues from cell spheroids is demonstrated by employing the vibration of acoustic standing waves and its hydrodynamic effect at the bottom of a liquid-carrier chamber. A large number of cell spheroids (>10(4) ) are assembled in seconds into a closely packed structure in a scaffold-free fashion under nodal pattern of the standing waves in a fluidic environment.

Indexed as

AcousticsAnimalsCells, CulturedCell SurvivalHepatocytesHumansHuman Umbilical Vein Endothelial CellsOrganoidsRatsSpheroids, CellularTissue Engineering3D co-culturecell spheroidsscaffold-free assemblyspheroid fusiontissue engineering

Identifiers

PMID26149464
PMCPMC4731612

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.