ArticleDeutsches Arzteblatt international2015
Fracture Risk and Risk Factors for Osteoporosis.
Article in Deutsches Arzteblatt international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 45 citations in OpenAlex.
- Differences in lumbar spine bone mineral density measured by quantitative computed tomography and dual-energy X-ray absorptiometry: an age- and sex-specific analysis.Journal of orthopaedic surgery and research · 2026Article
- The influence of severity of hemophilia on bone mineral density and fracture risk.Research and practice in thrombosis and haemostasis · 2024Article
- Mediterranean diet in the targeted prevention and personalized treatment of chronic diseases: evidence, potential mechanisms, and prospects.The EPMA journal · 2024Review
- Uncharted Territories: Dynamic Hip Screw Migration Into the Pelvis Requiring Laparotomy.Cureus · 2024Article
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- Sex Difference in the Association between Prior Fracture and Subsequent Risk of Incident Dementia: A Longitudinal Cohort Study.The journal of prevention of Alzheimer's disease · 2024Article
- Examining the Health-Related Needs of Females during Menopause: A Systematic Review Study.Journal of menopausal medicine · 2023Review
- Cumulative exposure to remnant cholesterol and the risk of fragility fractures: a longitudinal cohort study.Frontiers in endocrinology · 2023Article
- Article
- Current concepts of the perioperative management of closed ankle fractures.Journal of perioperative practice · 2022Review
- Identification of osteoporosis based on gene biomarkers using support vector machine.Open medicine (Warsaw, Poland) · 2022Article
- Anticonvulsant use and bone health in a population-based study of men and women: cross-sectional data from the Geelong Osteoporosis Study.BMC musculoskeletal disorders · 2021Article
- A Longitudinal Study of Lumbar Sagittal Change in Middle-Aged Healthy Volunteers.Spine surgery and related research · 2021Article
- A Study of Risk Factors for Early-Onset Adjacent Vertebral Fractures After Kyphoplasty.Global spine journal · 2020Article
- The Membrane Transporter OAT7 (SLC22A9) Is Not a Susceptibility Factor for Osteoporosis in Europeans.Frontiers in endocrinology · 2020Article
- Clinical Characteristics of Primary and Secondary Osteoporotic Fractures: Data from Single Referral Center Emergency Department.Journal of bone metabolism · 2019Article
- Beneficial effects of Cuscuta chinensis extract on glucocorticoid-induced osteoporosis through modulation of RANKL/OPG signals.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2019Article
- Comparison of implant survivability in primary 1- to 2-level lumbar fusion amongst opioid abusers and non-opioid abusers.Journal of spine surgery (Hong Kong) · 2018Article
- Morin protects glucocorticoid-induced osteoporosis through regulating the mitogen-activated protein kinase signaling pathway.Journal of natural medicines · 2018Article
- Targeting sphingosine-1-phosphate lyase as an anabolic therapy for bone loss.Nature medicine · 2018Article
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Authors and funding
6 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAs the population ages, diseases of the elderly are becoming more common, including osteoporosis. Ways to assess the risk of fracture and the distribution and effects of known risk factors for osteoporosis will be important in planning for future healthcare needs, as well as in the development of preventive strategies.
methodsThe study population included 6029 men and women aged 20-90 who underwent examination in the second follow-up wave of the Study of Health in Pomerania (SHIP-2) or in the basal SHIP-Trend Study. The risk of fracture was estimated on the basis of quantitative ultrasonography of the calcaneus. Prior fractures and risk factors for osteoporosis were ascertained in standardized interviews.
results4.6% of the male subjects and 10.6% of the female subjects were judged to have an elevated risk of fracture. The corresponding percentages among subjects over age 65 were 8.8% for men and 28.2% for women. Even among subjects under age 55, risk factors for osteoporosis were associated with lower bone stiffness: the mean stiffness index was 103/98 (men/women) without risk factors, 99/96 with one risk factor, and 93/95 with more than one risk factor. Logistic regression analysis yielded an odds ratio of 1.89 (95% confidence interval: 1.44-2.50; p<0.01) for prevalent fractures among subjects aged 75 and older compared to subjects under age 55.
conclusionThe data indicate a high prevalence of osteoporosis from age 65 onward. These findings are consistent with those of other studies from Germany and across Europe. Younger men and women should already begin taking steps to counteract modifiable risk factors.
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