Observational studyClinical anatomy (New York, N.Y.)2015
Meniscal extrusion or subchondral damage characterize incident accelerated osteoarthritis: Data from the Osteoarthritis Initiative.
Observational study in Clinical anatomy (New York, N.Y.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed, 39 citations in OpenAlex.
- Simplified Centralization Technique With Dual-Tunnel Meniscal Root Repair.Arthroscopy techniques · 2025Article
- The use of lateral wedge insoles delays osteoarthritis progression and improves clinical outcomes in medial meniscus posterior root repair.Journal of experimental orthopaedics · 2025Article
- Meniscal extrusion: Proposal for a novel qualitative classification.Journal of experimental orthopaedics · 2025Review
- Radiomic features of the medial meniscus predicts incident destabilizing meniscal tears: Data from the osteoarthritis initiative.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2024Article
- Extrusion of the anterior segment of the medial meniscus extrusion initiates knee osteoarthritis: evaluation using magnetic resonance imaging.Journal of experimental orthopaedics · 2023Article
- Meniscal degeneration is prognostic of destabilzing meniscal tear and accelerated knee osteoarthritis: Data from the Osteoarthritis Initiative.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2023Article
- Meniscal extrusion: risk factors and diagnostic tools to predict early osteoarthritis.Orthopedic reviews · 2023Article
- Clinical significance and management of meniscal extrusion in different knee pathologies: a comprehensive review of the literature and treatment algorithm.Knee surgery & related research · 2022Review
- Article
- Risk factors and the natural history of accelerated knee osteoarthritis: a narrative review.BMC musculoskeletal disorders · 2020Review
- Longitudinal MRI structural findings observed in accelerated knee osteoarthritis: data from the Osteoarthritis Initiative.Skeletal radiology · 2019Observational
- Characterization and Comparison of Postnatal Rat Meniscus Stem Cells at Different Developmental Stages.Stem cells translational medicine · 2019Article
- Role of Magnetic Resonance Imaging in Classifying Individuals Who Will Develop Accelerated Radiographic Knee Osteoarthritis.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2019Observational
- Accelerated knee osteoarthritis is associated with pre-radiographic degeneration of the extensor mechanism and cruciate ligaments: data from the Osteoarthritis Initiative.BMC musculoskeletal disorders · 2019Article
- Early pre-radiographic structural pathology precedes the onset of accelerated knee osteoarthritis.BMC musculoskeletal disorders · 2019Article
- Diffuse tibiofemoral cartilage change prior to the development of accelerated knee osteoarthritis: Data from the osteoarthritis initiative.Clinical anatomy (New York, N.Y.) · 2019Article
- Characteristics of Accelerated Hand Osteoarthritis: Data from the Osteoarthritis Initiative.The Journal of rheumatology · 2019Article
- Effusion-synovitis and infrapatellar fat pad signal intensity alteration differentiate accelerated knee osteoarthritis.Rheumatology (Oxford, England) · 2019Article
- Association Between Declining Walking Speed and Increasing Bone Marrow Lesion and Effusion Volume in Individuals with Accelerated Knee Osteoarthritis.Arthritis care & research · 2019Article
- A Comprehensive Review of the Fabella Bone.Cureus · 2018Review
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 1 country.
Funding
Abstract
Knee osteoarthritis (KOA) is typically a slowly progressive disorder; however, a subset of knees progress with dramatic rapidity. We aimed to describe magnetic resonance imaging (MRI) findings that are associated with accelerated KOA. We conducted a longitudinal descriptive study in the Osteoarthritis Initiative cohort. We selected participants who had no radiographic KOA at baseline with one of the following in the most severe knee: (1) accelerated KOA (progressed to end-stage KOA within 48 months), (2) common KOA, and (3) no KOA at all visits. We enriched the sample by selecting knees with a self-reported or suspected knee injury. A musculoskeletal radiologist blinded to group assignments but not to time sequence performed MRI readings for the visit before and after an injury. We assessed 38 participants (knees), 66% were female, mean age 61 (9) years, and mean body mass index 28.5 (4.9) kg/m(2). Fifteen of 20 knees with no or common KOA, had no incident findings consistent with acute damage. Among the 18 knees with accelerated KOA most had incident findings: 13 (72%) had incident medial meniscal pathology with extrusion and 5 (28%) knees had subchondral damage. Incident MRI findings that are associated with incident accelerated KOA are characterized by structural damage that compromises subchondral bone or the function of the meniscus. Recognizing meniscal extrusion and/or change in shape, lateral meniscal tear, or acute subchondral damage may be vital for identifying individuals at risk for accelerated KOA.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.