Evidence map›Paper›PMID 26148520›Full record

ArticleWorld journal of surgery2015

Topical Steroids Are Effective in the Treatment of Idiopathic Granulomatous Mastitis.

Fatih Altintoprak, Taner Kivilcim, Omer Yalkin, Yener Uzunoglu, Zeynep Kahyaoglu, Osman Nuri Dilek

3 registry-linked trialsAbstract read
PubMed Publisher
In one paragraph

Article in World journal of surgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 31 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 3 pooled it
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02959580 phase4unknown statusnot on this mapstarted 2017, after this paper: background citation

Evaluation of Topical Steroids and Surgical Treatment for Idiopathic Granulomatous Mastitis

TypeinterventionalSponsorPeking Union Medical College HospitalRan2017 to 2020Enrolled100ConditionsGranulomatous MastitisArmsHydrocortisone Butyrate, extended excision
NCT03766997 phase4unknown statusnot on this mapstarted 2019, after this paper: background citation

A Randomized Controlled Study on the Effectiveness of Local Injection Combined With Topical Steroids vs. Topical Steroids Mono-therapy in the Treatment of Idiopathic Granulomatous Mastitis

TypeinterventionalSponsorPeking Union Medical College HospitalRan2019 to 2022Enrolled100ConditionsGranulomatous MastitisArmsCompound Betamethasone Injection, Hydrocortisone Butyrate 0.1% Cream
NCT06985537 phase1not yet recruitingnot on this mapstarted 2025, after this paper: background citation

Efficacy of Ultrasound Guided Intralesional Steroid Injection in Idiopathic Granulomatous Mastitis (IGM)

TypeinterventionalSponsorAssiut UniversityRan2025 to 2026Enrolled40ConditionsIdiopathic Granulomatous MastitisArmsUltrasound guided intralesional Steroids injection (Triamicinolone)
3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 3 syntheses or guidelines pooled it, 71 citations in OpenAlex.

  1. Pooled it
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  11. Imiquimod as a new treatment in refractory idiopathic granulomatous mastitis: report of two cases.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2024
    Article
  12. Article
  13. Idiopathic Granulomatous Mastitis.The breast journal · 2024
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Fatih AltintoprakDepartment of General Surgery, Faculty of Medicine, Sakarya University, Sakarya, Turkey. fatihaltintoprak@yahoo.com.
Taner KivilcimDepartment of General Surgery, Research and Educational Hospital, Sakarya University, Sakarya, Turkey.
Omer YalkinDepartment of General Surgery, Research and Educational Hospital, Sakarya University, Sakarya, Turkey.
Yener UzunogluDepartment of General Surgery, Research and Educational Hospital, Sakarya University, Sakarya, Turkey.
Zeynep KahyaogluDepartment of Pathology, Research and Educational Hospital, Sakarya University, Sakarya, Turkey.
Osman Nuri DilekDepartment of General Surgery, Faculty of Medicine, Sakarya University, Sakarya, Turkey.
Sakarya University · TRIzmir Kâtip Çelebi University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIdiopathic granulomatous mastitis (IGM) is a rare, benign, and chronic disease of the breast. Despite the various treatment approaches described for this disease, a gold standard treatment modality has not yet been defined. In this study, the effect of topical steroids was reviewed and assessed in patients with IGM.

methodsThe records of patients with IGM who were treated only with topical steroids were retrospectively reviewed. Patients were grouped as "completely healed," "inadequately healed," "stable," "worsened," or "recurred" if they had once healed but their symptoms returned. Patients whose skin changes were completely ameliorated were considered "completely healed."

resultsAll of the patients were women, and the average patient age was 35.7 years (range 24-48 years). During the average follow-up of 37.2 months (range 12-72 months) in patients who received only topical steroid treatment, recurrence was observed in three patients (3/28, 10.7 %), and no side effects or steroid-related complications occurred.

conclusionsTopical steroids seem to be effective in the treatment of IGM characterized by skin changes. Prospective clinical studies would be useful in determining the clinical efficacy of topical steroids in the treatment of IGM.

Indexed as

Administration, CutaneousAdultFemaleGranulomatous MastitisHumansMiddle AgedRecurrenceRetrospective StudiesSteroidsTreatment OutcomeYoung AdultSteroids

Identifiers

PMID26148520
OpenAlexW747099555

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.