ArticleCritical care (London, England)2015
Quantifying the healthcare costs of treating severely bleeding major trauma patients: a national study for England.
Article in Critical care (London, England), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Early high-dose cryoprecipitate to reduce mortality in adult patients with traumatic haemorrhage: the CRYOSTAT-2 RCT with cost-effectiveness analysis.Health technology assessment (Winchester, England) · 2024Trial
- Cost-effectiveness evaluation of the PROPPR trial transfusion protocols.Transfusion · 2020Trial
- Analysis of prognosis and medical resource utilization in elderly patients with trauma: A retrospective cohort study in one trauma center.Journal of the Chinese Medical Association : JCMA · 2026Article
- Article
- Characteristics and outcomes of geriatric injuries presenting to an urban emergency department in Ghana.African journal of emergency medicine : Revue africaine de la medecine d'urgence · 2025Article
- Utility of point of care viscoelastic haemostatic assays for trauma patients in the emergency department.Scandinavian journal of trauma, resuscitation and emergency medicine · 2025Observational
- An economic evaluation of triage tools for patients with suspected severe injuries in England.BMC emergency medicine · 2022Article
- Severe thoracic or abdominal injury in major trauma patients can safely be ruled out by "Valutazione Integrata Bed Side" evaluation without total body CT scan.Irish journal of medical science · 2021Article
- The costs of traumatic head injury and associated factors at University of Gondar Specialized Referral Hospital, Northwest Ethiopia.BMC public health · 2019Article
- A one-year cost-utility analysis of REBOA versus RTACC for non-compressible torso haemorrhage.Trauma (London, England) · 2019Article
- Multiple Trauma and Emergency Room Management.Deutsches Arzteblatt international · 2017Article
- The evaluation of enhanced feedback interventions to reduce unnecessary blood transfusions (AFFINITIE): protocol for two linked cluster randomised factorial controlled trials.Implementation science : IS · 2017Article
- The European guideline on management of major bleeding and coagulopathy following trauma: fourth edition.Critical care (London, England) · 2016Article
- Role of the RAGE Axis during the Immune Response after Severe Trauma: A Prospective Pilot Study.Mediators of inflammation · 2015Article
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Authors and funding
12 authors.
Funding
Abstract
introductionSeverely bleeding trauma patients are a small proportion of the major trauma population but account for 40% of all trauma deaths. Healthcare resource use and costs are likely to be substantial but have not been fully quantified. Knowledge of costs is essential for developing targeted cost reduction strategies, informing health policy, and ensuring the cost-effectiveness of interventions.
methodsIn collaboration with the Trauma Audit Research Network (TARN) detailed patient-level data on in-hospital resource use, extended care at hospital discharge, and readmissions up to 12 months post-injury were collected on 441 consecutive adult major trauma patients with severe bleeding presenting at 22 hospitals (21 in England and one in Wales). Resource use data were costed using national unit costs and mean costs estimated for the cohort and for clinically relevant subgroups. Using nationally available data on trauma presentations in England, patient-level cost estimates were up-scaled to a national level.
resultsThe mean (95% confidence interval) total cost of initial hospital inpatient care was £19,770 (£18,177 to £21,364) per patient, of which 62% was attributable to ventilation, intensive care, and ward stays, 16% to surgery, and 12% to blood component transfusion. Nursing home and rehabilitation unit care and re-admissions to hospital increased the cost to £20,591 (£18,924 to £22,257). Costs were significantly higher for more severely injured trauma patients (Injury Severity Score ≥15) and those with blunt injuries. Cost estimates for England were £148,300,000, with over a third of this cost attributable to patients aged 65 years and over.
conclusionsSeverely bleeding major trauma patients are a high cost subgroup of all major trauma patients, and the cost burden is projected to rise further as a consequence of an aging population and as evidence continues to emerge on the benefits of early and simultaneous administration of blood products in pre-specified ratios. The findings from this study provide a previously unreported baseline from which the potential impact of changes to service provision and/or treatment practice can begin to be evaluated. Further studies are still required to determine the full costs of post-discharge care requirements, which are also likely to be substantial.
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