ArticleBMC neurology2015
Ultrasound measurement of optic nerve diameter and optic nerve sheath diameter in healthy Chinese adults.
Article in BMC neurology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05335902 (The Influence of Extracorporeal Circulation During Cardiac Surgery on Optic Nerve Sheath Diameter), which is not on this map. Cited by 33 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Influence of Extracorporeal Circulation During Cardiac Surgery on Optic Nerve Sheath Diameter
Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it, 75 citations in OpenAlex.
- B-mode transorbital ultrasonography for the diagnosis of idiopathic intracranial hypertension: an updated systematic review and meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2023Pooled it
- Correlation of optic nerve sheath diameter with directly measured intracranial pressure in Korean adults using bedside ultrasonography.PloS one · 2017Trial
- Towards a Deeper Understanding of Cerebrospinal Fluid Transport in the Optic Nerve Subarachnoid Space: A Computational Approach.Annals of biomedical engineering · 2026Article
- Article
- Optic nerve sheath diameter measurement in healthy South Iranian adults from a cross-sectional ultrasonographic study.Scientific reports · 2025Article
- Related studies on measuring the normal values of optic nerve sheath diameter in healthy Chinese adults based on CT scans.Scientific reports · 2025Article
- Non-invasive estimation of cerebrospinal fluid pressure in idiopathic intracranial hypertension: magnetic resonance imaging analysis of optic nerve and eyeball.Acta neurologica Belgica · 2025Article
- The predictive value of optic nerve sheath diameter measurement via ultrasound for intracerebral hemorrhage complicated by cerebral-cardiac syndrome.BMC neurology · 2025Article
- Deep learning based optic nerve sheath diameter characterization and structure quantification on transorbital ultrasound images.Frontiers in medicine · 2025Article
- The optic nerve sheath in hypertensive disorders of pregnancy and perinatal outcomes: a cohort study.BMC pregnancy and childbirth · 2024Article
- Quantitative ultrasound image assessment of the optic nerve subarachnoid space during 90-day head-down tilt bed rest.NPJ microgravity · 2024Article
- Variability of the optic nerve sheath diameter on brain computed tomography in Turkish children based on sex and age.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023Article
- Diagnostic Value of the Combination of Ultrasonographic Optic Nerve Sheath Diameter and Width of Crural Cistern with Respect to the Intracranial Pressure in Patients Treated with Decompressive Craniotomy.Neurocritical care · 2023Observational
- Optic Nerve Sheath Diameter: A Cross-Sectional Study of Ultrasonographic Measurement in Healthy Black South African Adults.Life (Basel, Switzerland) · 2023Article
- Non-Invasive Intracranial Pressure Monitoring.Journal of clinical medicine · 2023Review
- Extracorporeal Circulation and Optic Nerve Ultrasound: A Pilot Study.Medicina (Kaunas, Lithuania) · 2023Article
- Ultrasound measurement of optic nerve sheath diameter in a healthy adult Colombian population.BMC neurology · 2023Article
- Optic nerve sheath diameter at high altitude: standardized measures in healthy volunteers.The ultrasound journal · 2022Article
- Optic nerve sheath diameter in severe preeclampsia with neurologic features versus controls.BMC pregnancy and childbirth · 2022Article
- Accuracy of Optic Nerve Sheath Diameter Measurements in Pocket-Sized Ultrasound Devices in a Simulation Model.Frontiers in medicine · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMeasurement of optic nerve sheath diameter (ONSD) is a fast and non-invasive method in detecting elevated intracranial pressure. However, the reported normal range of ONSD was inconsistent. The objective of the study was to determine the normal range of ONSD in healthy Chinese adults.
methodsEyeball transverse diameter (ETD), optic nerve diameter (OND), and ONSD were measured by ultrasound examination in healthy adult volunteers. The OND and ONSD were assessed 3 mm behind the globe. The section showing maximal transverse diameter of the eyeball was frozen and the diameter was measured. Each ETD, OND and ONSD was examined twice and the mean value was calculated.
resultsA total of 519 healthy volunteers were included in the study. The median (interquartile range) of ETD, OND and ONSD were 22.3 (21.6 to 23.1) mm, 3.2 (2.9 to 3.4) mm, and 5.1 (4.7 to 5.4) mm, respectively. The 95% percentile of ONSD was 5.9 mm. There was no significant difference in ETD, OND or ONSD between male and female, or between left and right eye. ONSD was significantly correlated with OND (r = 0.62, P < 0.001), and the median OND/ONSD ratio (interquartile range) was 0.63 (0.59 to 0.67).
conclusionsThe median and the 95% percentile of sonographic measurement of ONSD are 5.1 mm and 5.9 mm in healthy Chinese adults. The ONSD is correlated with OND, while independent of gender, age, height, weight and ETD. The median OND/ONSD ratio is 0.63 and this parameter warrants further investigation in patients with brain injury.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.