Evidence map›Paper›PMID 26147538›Full record

ArticleJournal of occupational and environmental medicine2015

Comparison of Acute Health Effects From Exposures to Diesel and Biodiesel Fuel Emissions.

Aaron A Mehus, Rustin J Reed, Vivien S T Lee, Sally R Littau, Chengcheng Hu, Eric A Lutz, Jefferey L Burgess

Abstract readComparative Study
In one paragraph

Article in Journal of occupational and environmental medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Trial
  4. Trial
  5. Article
  6. Review
  7. Article
  8. Article
  9. Evaluation of fireground exposures using urinary PAH metabolites.Journal of exposure science & environmental epidemiology · 2021
    Article
  10. Biomarkers after Controlled Inhalation Exposure to Exhaust from Hydrogenated Vegetable Oil (HVO).International journal of environmental research and public health · 2021
    Article
  11. Viruses and non-allergen environmental triggers in asthma.Journal of investigative medicine : the official publication of the American Federation for Clinical Research · 2019
    Review
  12. Review
  13. Fine-Scale Source Apportionment Including Diesel-Related Elemental and Organic Constituents of PMInternational journal of environmental research and public health · 2018
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Aaron A MehusFrom the Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson.
Rustin J Reed
Vivien S T Lee
Sally R Littau
Chengcheng Hu
Eric A Lutz
Jefferey L Burgess

Funding

VITAMIN AP30CA023074 · NCI · UNIVERSITY OF ARIZONA · PI Dan Theodorescu · 1985 to 2026
$110.2M
SOUTHWEST ENVIRONMENTAL HEALTH SCIENCES CENTERP30ES006694 · NIEHS · UNIVERSITY OF ARIZONA · PI DEAN BILLHEIMER · 1994 to 2026
$36.7M
Training in Environmental Toxicology of Human DiseaseT32ES007091 · NIEHS · UNIVERSITY OF ARIZONA · PI Nathan J Cherrington · 1985 to 2026
$10.7M
Comparison of Diesel and Biodiesel Emissions and Health Effects in Underground MiR01OH009878 · OH · UNIVERSITY OF ARIZONA · PI BURGESS, JEFFEREY L. · 2012 to 2014
$1.4M
Acquisition of a LTQ Orbitrap XL ETD Hybrid FT Mass SpectrometerS10RR028868 · NCRR · UNIVERSITY OF ARIZONA · PI TSAPRAILIS, GEORGE · 2010 to 2010
$916k
NCI NIH HHS CA023074NCI NIH HHS P30 CA023074NCRR NIH HHS 1S10 RR028868-01NCRR NIH HHS S10 RR028868NIEHS NIH HHS ES06694NIEHS NIH HHS P30 ES006694NIEHS NIH HHS T32 ES007091NIOSH CDC HHS R01 OH009878
6 · The paper itself

Abstract

objectiveTo investigate the comparative acute health effects associated with exposures to diesel and 75% biodiesel/25% diesel (B75) blend fuel emissions.

methodsWe analyzed multiple health endpoints in 48 healthy adults before and after exposures to diesel and B75 emissions in an underground mine setting-lung function, lung and systemic inflammation, novel biomarkers of exposure, and oxidative stress were assessed.

resultsB75 reduced respirable diesel particulate matter by 20%. Lung function declined significantly more after exposure to diesel emissions. Lung inflammatory cells along with sputum and plasma inflammatory mediators increased significantly to similar levels with both exposures. Urinary 8-hydroxydeoxyguanosine, a marker of oxidative stress, was not significantly changed after either exposure.

conclusionsUse of B75 lowered respirable diesel particulate matter exposure and some associated acute health effects, although lung and systemic inflammation were not reduced compared with diesel use.

Indexed as

BiofuelsGasolineMiningAdultAir Pollutants, OccupationalAir Pollution, IndoorBiomarkersEndpoint DeterminationEnvironmental MonitoringFemaleHealthy VolunteersHumansInhalation ExposureMaleOccupational ExposureOxidative StressAir Pollutants, OccupationalBiofuelsBiomarkersGasolineParticulate MatterVehicle Emissions

Identifiers

PMID26147538
PMCPMC4479787

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.