ArticlePloS one2015
Eight Year Prospective Study of Adenoviruses Infections in Hospitalized Children. Comparison with Other Respiratory Viruses.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed, 30 citations in OpenAlex.
- Impact of Nirsevimab on RSV and Non-RSV Severe Respiratory Infections in Hospitalized Infants.Influenza and other respiratory viruses · 2025Article
- Screening and verification of differentially expressed serum proteins in children with severe adenovirus pneumonia.Frontiers in public health · 2024Article
- Antibiotic Utilization in Hospitalized Children with Bronchiolitis: A Prospective Study Investigating Clinical and Epidemiological Characteristics at a Secondary Hospital in Madrid (2004-2022).Pathogens (Basel, Switzerland) · 2023Article
- Molecular subtypes of Adenovirus-associated acute respiratory infection outbreak in children in Northern Vietnam and risk factors of more severe cases.PLoS neglected tropical diseases · 2023Article
- Epidemiological characteristics of four common respiratory viral infections in children.Virology journal · 2021Article
- Article
- Viral pathogens associated with acute lower respiratory tract infections in children younger than 5 years of age in Bulgaria.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2019Article
- New Adenovirus Groups in Western Palaearctic Bats.Viruses · 2018Article
- Short-term relevance of lower respiratory viral coinfection in inpatients under 2 years of age.Anales de pediatria · 2018Article
- [Short-term relevance of lower respiratory viral coinfection in inpatients under 2 years of age].Anales de pediatria · 2018Observational
- Clinical and molecular features of adenovirus type 2, 3, and 7 infections in children in an outbreak in Taiwan, 2011.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2017Article
- [Epidemiological analysis of 440 cases of respiratory adenovirus infections in children from the Suzhou area between 2006 and 2015].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2017Article
- Molecular Epidemiology and Clinical Manifestations of Adenovirus Respiratory Infections in Taiwanese Children.Medicine · 2016Article
- Respiratory Infections by Enterovirus D68 in Outpatients and Inpatients Spanish Children.The Pediatric infectious disease journal · 2016Article
- Fatal adenovirus pneumonia in a 15-day-old infant despite extracorporeal life support treatment: A case report.Medicine internationalArticle
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Human adenovirus (HAdV) cause upper and lower respiratory tract infections. However, there are few large prospective studies focused on HAdVs acute infections requiring hospitalization. From 2005 to 2013 a prospective study was conducted on children admitted with acute respiratory infections. Specimens of nasopharyngeal aspirate were taken for virological study by PCR and clinical data was recorded. HAdV specimens were genotyped. Frequency and clinical course of HAdV infections were compared with RSV, rhinovirus (RV), human bocavirus (HBoV) and influenza in the same population. HAdV was detected in 403 cases of 2371 confirmed viral infections (17.2%) , of which 154 were single virus infections (38%). We genotyped 154 HAdVs. The most frequent genotypes were HAdV-3 (24%), HAdV-6 (21%), and HAdV-5 (20%). A total of 262 children had fever (64.9%); 194 suffered hypoxia (48%), and 147 presented infiltrate in chest x-rays (36.4%). The most frequent diagnoses were recurrent wheezing or asthma (51.7%), bronchiolitis (18.3 %), and pneumonia (11.9%), and 46 (11.4%) episodes required prolonged hospitalization (>7 days) due to the severity. Adenovirus single infections were compared with single infections of 598 RSV, 494 RV, 83 influenza and 78 HBoV. Significant clinical differences were found between HAdV, RSV and RV infections.
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