Trial reportPloS one2015
PARADISE 24: A Measure to Assess the Impact of Brain Disorders on People's Lives.
Trial report in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 3 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Risk factors associated to disability in primary headaches: a systematic review to inform future iterations of the Global Burden of Disease Study.The journal of headache and pain · 2025Pooled it
- Psychosocial wellbeing of people with dementia: systematic review and construct analysis.Acta neuropsychiatrica · 2025Pooled it
- All metrics are equal, but some metrics are more equal than others: A systematic search and review on the use of the term 'metric'.PloS one · 2018Pooled it
- Factors Predicting Response to the Recovery-Oriented Cognitive Behavioural Workshop for Persons Diagnosed with Schizophrenia.Community mental health journal · 2020Trial
- Article
- The definition of treatment resistance in anxiety disorders: a Delphi method-based consensus guideline.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2024Article
- WHO Functioning and Disability Disaggregation (FDD11) tool: a reliable approach for disaggregating data by disability.Archives of public health = Archives belges de sante publique · 2022Article
- Validation of PARADISE 24 and Development of PARADISE-EDEN 36 in Patients with Dementia.International journal of environmental research and public health · 2022Article
- Integrated care model and point of care diagnostics facilitate Hepatitis C treatment among patients receiving opioid agonist therapy: a retrospective review of medical records.Substance abuse treatment, prevention, and policy · 2022Article
- Fatigue after acquired brain injury impacts health-related quality of life: an exploratory cohort study.Scientific reports · 2021Article
- Psychosocial difficulties and treatment retention in inpatient detoxification programmes.Nordisk alkohol- & narkotikatidskrift : NAT · 2021Article
- Challenges in Documenting Non-Fatal Drowning Disability in Bangladesh: A Community-Based Survey.International journal of environmental research and public health · 2021Article
- Psychometric Properties of the Persian Version of the PARADISE-24 Questionnaire.International journal of preventive medicine · 2021Article
- A Response to: Comparison of Psychological Difficulties in Patients with Migraine and Epilepsy Using PARADISE-24 Questionnaire [Letter].Journal of multidisciplinary healthcare · 2020Article
- Comparison of Psychological Difficulties in Patients with Migraine and Epilepsy Using PARADISE-24 Questionnaire.Journal of multidisciplinary healthcare · 2020Article
- Social Mind and Long-Lasting Disease: Focus on Affective and Cognitive Theory of Mind in Multiple Sclerosis.Frontiers in psychology · 2019Article
- Utility of functioning in predicting costs of care for patients with mood and anxiety disorders: a prospective cohort study.International clinical psychopharmacology · 2017Article
- Psychosocial difficulties in patients with episodic migraine: a cross-sectional study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2016Article
- Internal and Predictive Validity of the French Health of the Nation Outcome Scales: Need for Future Directions.PloS one · 2016Article
- Cross-sectional associations of depressive symptom severity and functioning with health service use by older people in low-and-middle income countries.International journal of environmental research and public health · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 7 institutions in 7 countries.
Funding
Abstract
objectiveTo construct a metric of the impact of brain disorders on people's lives, based on the psychosocial difficulties (PSDs) that are experienced in common across brain disorders. STUDY
designPsychometric study using data from a cross-sectional study with a convenience sample of 722 persons with 9 different brain disorders interviewed in four European countries: Italy, Poland, Spain and Finland. Questions addressing 64 PSDs were first reduced based on statistical considerations, patient's perspective and clinical expertise. Rasch analyses for polytomous data were also applied.
settingIn and outpatient settings.
resultsA valid and reliable metric with 24 items was created. The infit of all questions ranged between 0.7 and 1.3. There were no disordered thresholds. The targeting between item thresholds and persons' abilities was good and the person-separation index was 0.92. Persons' abilities were linearly transformed into a more intuitive scale ranging from zero (no PSDs) to 100 (extreme PSDs).
conclusionThe metric, called PARADISE 24, is based on the hypothesis of horizontal epidemiology, which affirms that people with brain disorders commonly experience PSDs. This metric is a useful tool to carry out cardinal comparisons over time of the magnitude of the psychosocial impact of brain disorders and between persons and groups in clinical practice and research.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.