ArticleJournal of abnormal psychology2015
Pupillary reactivity to sad stimuli as a biomarker of depression risk: Evidence from a prospective study of children.
Article in Journal of abnormal psychology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
29 citing papers in PubMed, 53 citations in OpenAlex.
- Age differences in electrocortical reactivity to fearful faces following aversive conditioning in youth.Journal of experimental child psychology · 2019Trial
- Transactional relations between attentional biases for affective stimuli and depressive symptoms in offspring of mothers with and without major depressive disorder.Journal of psychopathology and clinical science · 2026Article
- Are depressive symptoms linked to a reduced pupillary response to novel positive information?-An eye tracking proof-of-concept study.Frontiers in psychology · 2024Article
- Parents regulate arousal while sharing experiences with their child: a study of pupil diameter change responses.Frontiers in human neuroscience · 2023Article
- A Web-Based Cognitive Behavioral Therapy, Mindfulness Meditation, and Yoga Intervention for Posttraumatic Stress Disorder: Single-Arm Experimental Clinical Trial.JMIR mental health · 2022Article
- Pupil responses to dynamic negative facial expressions of emotion in infants and parents.Developmental psychobiology · 2021Article
- Quantitative Infrared Pupillometry in Nonconvulsive Status Epilepticus.Neurocritical care · 2021Observational
- Contribution of Eye-Tracking to Study Cognitive Impairments Among Clinical Populations.Frontiers in psychology · 2021Article
- Pupil Dilation during Reward Anticipation Is Correlated to Depressive Symptom Load in Patients with Major Depressive Disorder.Brain sciences · 2020Article
- Pupil Response to Affective Stimuli: a Biomarker of Early Conduct Problems in Young Children.Journal of abnormal child psychology · 2020Article
- Pupillary reactivity to alcohol cues as a predictive biomarker of alcohol relapse following treatment in a pilot study.Psychopharmacology · 2019Article
- Children's sustained attention to emotional facial expressions and their autonomic nervous system reactivity during parent-child interactions.Biological psychology · 2019Article
- A multimethod screening approach for pediatric depression onset: An incremental validity study.Journal of consulting and clinical psychology · 2019Article
- Episodic Life Stress and the Development of Overgeneral Autobiographical Memory to Positive Cues in Youth.Journal of abnormal child psychology · 2018Article
- Pupil Mimicry is the Result of Brightness Perception of the Iris and Pupil.Journal of cognition · 2018Article
- Cognitive Reappraisal and Depression in Children with a Parent History of Depression.Journal of abnormal child psychology · 2018Article
- Parental Expressed Emotion-Criticism and Neural Markers of Sustained Attention to Emotional Faces in Children.Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53 · 2018Article
- Pupillary Responses to Robotic and Human Emotions: The Uncanny Valley and Media Equation Confirmed.Frontiers in psychology · 2018Article
- Biobehavioral assessment of the anxiety disorders: Current progress and future directions.World journal of psychiatry · 2017Review
- Increased pupil dilation to angry faces predicts interpersonal stress generation in offspring of depressed mothers.Journal of child psychology and psychiatry, and allied disciplines · 2017Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
The primary aim of the current study was to examine whether physiological reactivity to depression-relevant stimuli, measured via pupil dilation, serves as a biomarker of depression risk among children of depressed mothers. Participants included 47 mother-child dyads. All mothers had a history of major depressive disorder. Pupil dilation was recorded while children viewed angry, happy, and sad faces. Follow-up assessments occurred 6, 12, 18, and 24 months after the initial assessment, during which structured interviews were used to assess for children's levels of depressive symptoms as well as the onset of depressive diagnoses. Children exhibiting relatively greater pupil dilation to sad faces experienced elevated trajectories of depressive symptoms across the follow-up as well as a shorter time to depression onset. These findings were not observed for children's pupillary reactivity to angry or happy faces. The current findings suggest that physiological reactivity to sad stimuli, assessed using pupillometry, serves as a potential biomarker of depression risk among children of depressed mothers. Notably, pupillometry is an inexpensive tool that could be administered in clinical settings, such as pediatricians' offices, to help identify which children of depressed mothers are at highest risk for developing depression themselves.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.