Evidence map›Paper›PMID 26147298›Full record

ArticlePloS one2015

A Cross-Sectional Study of the Cardiovascular Effects of Welding Fumes.

Huiqi Li, Maria Hedmer, Monica Kåredal, Jonas Björk, Leo Stockfelt, Håkan Tinnerberg, Maria Albin, Karin Broberg

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 50 citations in OpenAlex.

  1. Review
  2. Article
  3. Longitudinal changes in cardiovascular disease-related proteins in welders.International archives of occupational and environmental health · 2024
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  5. Review
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  10. Effect of welding fumes on the cardiovascular system: a six-year longitudinal study.Scandinavian journal of work, environment & health · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Huiqi LiDivision of Occupational and Environmental Medicine, Laboratory Medicine, Lund University, Lund, Sweden.
Maria HedmerDivision of Occupational and Environmental Medicine, Laboratory Medicine, Lund University, Lund, Sweden.
Monica KåredalDivision of Occupational and Environmental Medicine, Laboratory Medicine, Lund University, Lund, Sweden.
Jonas BjörkCompetence Centre for Clinical Research, Lund University, Lund, Sweden.
Leo StockfeltDepartment of Occupational and Environmental Medicine, Sahlgrenska University Hospital and Academy, University of Gothenburg, Gothenburg, Sweden.
Håkan TinnerbergDivision of Occupational and Environmental Medicine, Laboratory Medicine, Lund University, Lund, Sweden.
Maria AlbinDivision of Occupational and Environmental Medicine, Laboratory Medicine, Lund University, Lund, Sweden.
Karin BrobergDivision of Occupational and Environmental Medicine, Laboratory Medicine, Lund University, Lund, Sweden; Unit of Metals & Health, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Lund University · SEKarolinska Institutet · SESahlgrenska University Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesOccupational exposure to particulate air pollution has been associated with an increased risk of cardiovascular disease. However, the risk to welders working today remains unclear. We aimed to elucidate the cardiovascular effects of exposure to welding fumes.

methodsIn a cross-sectional study, structured interviews and biological sampling were conducted for 101 welders and 127 controls (all non-smoking males) from southern Sweden. Personal breathing zone sampling of respirable dust was performed. Blood pressure (BP) and endothelial function (using peripheral arterial tonometry) were measured. Plasma and serum samples were collected from peripheral blood for measurement of C-reactive protein, low-density lipoprotein, homocysteine, serum amyloid A, and cytokines.

resultsWelders were exposed to 10-fold higher levels of particles than controls. Welders had significantly higher BP compared to controls, an average of 5 mm Hg higher systolic and diastolic BP (P ≤ 0.001). IL-8 was 3.4 ng/L higher in welders (P=0.010). Years working as a welder were significantly associated with increased BP (β=0.35, 95%CI 0.13 - 0.58, P=0.0024 for systolic BP; β=0.32, 95%CI 0.16 - 0.48, P<0.001 for diastolic BP, adjusted for BMI) but exposure to respirable dust was not associated with BP. No clear associations occurred between welding and endothelial function, or other effect markers.

conclusionsA modest increase in BP was found among welders compared to controls suggesting that low-to-moderate exposure to welding fumes remains a risk factor for cardiovascular disease.

Indexed as

WeldingAdultAir Pollutants, OccupationalBlood PressureC-Reactive ProteinCross-Sectional StudiesCytokinesEndothelium, VascularHumansInhalation ExposureLipoproteins, LDLMaleMiddle AgedOccupational DiseasesOccupational ExposureRisk FactorsAir Pollutants, OccupationalC-Reactive ProteinCytokinesLipoproteins, LDL

Identifiers

PMID26147298
PMCPMC4492943
OpenAlexW1945002561

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.