Evidence map›Paper›PMID 26146643›Full record

ReviewJournal of immunology research2015

Vaccines for TB: Lessons from the Past Translating into Future Potentials.

Gee Jun Tye, Min Han Lew, Yee Siew Choong, Theam Soon Lim, Maria Elena Sarmiento, Armando Acosta, Mohd Nor Norazmi

Open access · goldAbstract readReview
In one paragraph

Review in Journal of immunology research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Molecular Targets Related Drug Resistance Mechanisms in MDR-, XDR-, and TDR-Frontiers in cellular and infection microbiology · 2018
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Gee Jun TyeInstitute for Research in Molecular Medicine, Universiti Sains Malaysia, 11800 Minden, Penang, Malaysia ; ADAPT Research Cluster, Centre for Research Initiatives, Clinical & Health Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia.
Min Han LewInstitute for Research in Molecular Medicine, Universiti Sains Malaysia, 11800 Minden, Penang, Malaysia.
Yee Siew ChoongInstitute for Research in Molecular Medicine, Universiti Sains Malaysia, 11800 Minden, Penang, Malaysia ; ADAPT Research Cluster, Centre for Research Initiatives, Clinical & Health Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia.
Theam Soon LimInstitute for Research in Molecular Medicine, Universiti Sains Malaysia, 11800 Minden, Penang, Malaysia ; ADAPT Research Cluster, Centre for Research Initiatives, Clinical & Health Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia.
Maria Elena SarmientoSchool of Health Sciences, Universiti Sains Malaysia, Health Campus, 16150 Kubang Kerian, Kelantan, Malaysia.
Armando AcostaInstitute for Research in Molecular Medicine, Universiti Sains Malaysia, 11800 Minden, Penang, Malaysia.
Mohd Nor NorazmiInstitute for Research in Molecular Medicine, Universiti Sains Malaysia, 11800 Minden, Penang, Malaysia ; ADAPT Research Cluster, Centre for Research Initiatives, Clinical & Health Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia ; School of Health Sciences, Universiti Sains Malaysia, Health Campus, 16150 Kubang Kerian, Kelantan, Malaysia.
Universiti Sains Malaysia · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Development of vaccines for infectious diseases has come a long way with recent advancements in adjuvant developments and discovery of new antigens that are capable of eliciting strong immunological responses for sterile eradication of disease. Tuberculosis (TB) that kills nearly 2 million of the population every year is also one of the highlights of the recent developments. The availability or not of diagnostic methods for infection has implications for the control of the disease by the health systems but is not related to the immune surveillance, a phenomenon derived from the interaction between the bacteria and their host. Here, we will review the immunology of TB and current vaccine candidates for TB. Current strategies of developing new vaccines against TB will also be reviewed in order to further discuss new insights into immunotherapeutic approaches involving adjuvant and antigens combinations that might be of potential for the control of TB.

Indexed as

AnimalsBCG VaccineHumansImmunityMycobacterium tuberculosisTuberculosisTuberculosis VaccinesBCG VaccineTuberculosis Vaccines

Identifiers

PMID26146643
PMCPMC4469767
OpenAlexW1581693471

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.