Evidence map›Paper›PMID 26146621›Full record

ArticleBioMed research international2015

Epidemiology of Neonatal Sepsis and Implicated Pathogens: A Study from Egypt.

Eman M Rabie Shehab El-Din, Mohamed M Adel El-Sokkary, Mohamed Reda Bassiouny, Ramadan Hassan

Registry-linked trialOpen access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BioMed research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03275090 (The Effects of Two Different Intravenous Lipid Emulsions on the Outcomes of Preterm Infants With Sepsis), which is not on this map. Cited by 97 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
97citing papers in PubMed, 12 pooled it
17.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03275090 phase4completednot on this mapstarted 2016, after this paper: background citation

The Effects of Two Different Intravenous Lipid Emulsions on the Outcomes of Preterm Infants With Sepsis: a Randomized Pilot Controlled Trial

TypeinterventionalSponsorMansoura University Children HospitalRan2016 to 2017Enrolled40ConditionsSepsis NewbornArmsSmoflipid ®
3 · Its place in the literature

Who cites it

97 citing papers in PubMed, 12 syntheses or guidelines pooled it, 263 citations in OpenAlex.

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  11. Risk Factors of Nosocomial Infection for Infants in Neonatal Intensive Care Units: A Systematic Review and Meta-Analysis.Medical science monitor : international medical journal of experimental and clinical research · 2019
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  18. A Rare Case Report of Nosocomial Urosepsis due toCase reports in infectious diseases · 2026
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37 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Eman M Rabie Shehab El-DinUnit of Drug Analysis, Mansoura University, Mansoura 35516, Egypt.
Mohamed M Adel El-SokkaryDepartment of Microbiology and Immunology, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt.
Mohamed Reda BassiounyDepartment of Pediatrics, Faculty of Medicine, Mansoura University, Mansoura 35516, Egypt.
Ramadan HassanDepartment of Microbiology and Immunology, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt.
Mansoura University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prospective analytic study was conducted in NICUs of three Egyptian Neonatal Network (EGNN) participants in Mansoura Hospitals in Egypt over a period of 18 months from March 2011 to August 2012. By using EGNN 28-day discharge form, all demographic, clinical, and laboratory data were recorded and studied. During the study period, 357 neonates were diagnosed as suspected sepsis with an incidence of 45.9% (357/778) among the admitted neonates at the three neonatal intensive care units. 344 neonates (sex ratio = 1.3:1) were enrolled in the study in which 152 (44.2%) were classified as early onset sepsis EOS (≤72 hr) and 192 (55.8%) as late onset sepsis LOS (>72 hr). Among the LOS cases, 33.9% (65/192) were caused by nosocomial infections. In 40.7% (140/344), sepsis was confirmed by positive blood culture. The total mortality rate for the proven neonatal sepsis was 51% (25/49) and 42.9% (39/91) for EOS and LOS, respectively. Coagulase negative staphylococci were predominant isolates in both EOS and LOS, followed by Klebsiella pneumoniae. Most of the bacterial isolates had low sensitivity to the commonly used empiric antibiotics. However, 70.1% (89/127) exhibited multidrug resistance. Best sensitivities among Gram-positive isolates were found against imipenem, ciprofloxacin, vancomycin, and amikacin.

Indexed as

Age of OnsetAnti-Bacterial AgentsChildCross InfectionEgyptFemaleHumansInfant, NewbornInfant, Newborn, DiseasesIntensive Care Units, NeonatalKlebsiella InfectionsKlebsiella pneumoniaeMaleSepsisStaphylococcal InfectionsStaphylococcusAnti-Bacterial Agents

Identifiers

PMID26146621
PMCPMC4471255
OpenAlexW1481065096

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.