Evidence map›Paper›PMID 26146586›Full record

ArticleJournal of data mining in genomics & proteomics

Ranking of Prokaryotic Genomes Based on Maximization of Sortedness of Gene Lengths.

A Bolshoy, B Salih, I Cohen, T Tatarinova

Abstract read
In one paragraph

Article in Journal of data mining in genomics & proteomics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Gene-Family Extension Measures and Correlations.Life (Basel, Switzerland) · 2016
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

A BolshoyDepartment of Evolutionary and Environmental Biology and Institute of Evolution, University of Haifa, Israel.
B SalihDepartment of Evolutionary and Environmental Biology and Institute of Evolution, University of Haifa, Israel ; Department of Computer Science, University of Haifa, Israel, Israel.
I CohenDepartment of Evolutionary and Environmental Biology and Institute of Evolution, University of Haifa, Israel ; The Tauber Bioinformatics Research Center at University of Haifa.
T TatarinovaChildren's Hospital Los Angeles, University of Southern California, Los Angeles, California, USA.

Funding

Populaton Pharmacokinetic Modeling and Optimal ControlR01GM068968 · NIGMS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI NEELY, MICHAEL N. · 2003 to 2015
$3.9M
Ontogeny of Voriconazole Pharmaockinetics and MetabolismR01HD070886 · NICHD · UNIVERSITY OF SOUTHERN CALIFORNIA · PI NEELY, MICHAEL N. · 2012 to 2016
$2.5M
Mechanisms of Hypothermic Neuroprotection in NeonatesR01HD070996 · NICHD · JOHNS HOPKINS UNIVERSITY · PI NORTHINGTON, FRANCES J · 2012 to 2016
$1.7M
NICHD NIH HHS R01 HD070886NICHD NIH HHS R01 HD070996NIGMS NIH HHS R01 GM068968
6 · The paper itself

Abstract

How variations of gene lengths (some genes become longer than their predecessors, while other genes become shorter and the sizes of these factions are randomly different from organism to organism) depend on organismal evolution and adaptation is still an open question. We propose to rank the genomes according to lengths of their genes, and then find association between the genome rank and variousproperties, such as growth temperature, nucleotide composition, and pathogenicity. This approach reveals evolutionary driving factors. The main purpose of this study is to test effectiveness and robustness of several ranking methods. The selected method of evaluation is measuring of overall sortedness of the data. We have demonstrated that all considered methods give consistent results and Bubble Sort and Simulated Annealing achieve the highest sortedness. Also, Bubble Sort is considerably faster than the Simulated Annealing method.

Indexed as

Combinatorial optimizationComputational biologyEvolutionGene lengthLOPISimulation Annealing

Identifiers

PMID26146586
PMCPMC4487784

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.