ArticleJournal of therapeutic ultrasound2015
Characterization and evaluation of tissue-mimicking gelatin phantoms for use with MRgFUS.
Article in Journal of therapeutic ultrasound, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.
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Who cites it
67 citing papers in PubMed.
- Impact of breast biopsy markers on magnetic resonance-guided focused ultrasound.International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2026Article
- Effect of spatial resolution and heating duration on accuracy of dynamic proton resonance frequency shift temperature measurement with k-space weighted image contrast reconstruction during focused ultrasound.Magnetic resonance imaging · 2026Article
- Development and validation of 3D-printed anatomically accurate liver model for endoscopic ultrasound-based endo-hepatology training (with video).Surgical endoscopy · 2026Article
- A Magnetic Resonance-Compatible Fiberoptic Temperature Sensor for Measuring Focused Ultrasound-Induced Heating Without Artifacts.Ultrasound in medicine & biology · 2026Article
- Multiphysical Characterization of a Tissue-Mimicking Phantom: Composition, Thermal Behavior, and Broadband Electromagnetic Properties from Visible to Terahertz and Microwave Frequencies.Materials (Basel, Switzerland) · 2026Article
- Multi-Layer Brain-Mimicking Phantom for Replicating Dura and Pia Membrane Dimpling and Rupture Properties During Neural Interface Implantation.bioRxiv : the preprint server for biology · 2026Article
- Design and characterisation of intervertebral disc mimicking phantoms for photoacoustic imaging.Photoacoustics · 2026Article
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- Delivery of Cavitation Therapy With a Modified Clinical Scanner: In Vitro Evaluation.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2025Article
- Design of a wasp-inspired biopsy needle capable of self-propulsion and friction-based tissue transport.Frontiers in bioengineering and biotechnology · 2024Article
- Evaluation of acoustic-thermal simulations of in vivo magnetic resonance guided focused ultrasound ablative therapy.International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2024Article
- Magnetic Resonance Acoustic Radiation Force Imaging (MR-ARFI) for the monitoring of High Intensity Focused Ultrasound (HIFU) ablation in anisotropic tissue.Magma (New York, N.Y.) · 2023Article
- Simultaneous proton resonance frequency TMagnetic resonance in medicine · 2023Article
- Brain-Mimicking Phantom for Photoablation and Visualization.... International Symposium on Medical Robotics. International Symposium on Medical Robotics · 2023Article
- Evaluation of a transbronchial cryoprobe for the ablation of pulmonary nodules: an in vitro pilot study.BMC pulmonary medicine · 2023Article
7 more citing papers are in PubMed but not listed here.
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Abstract
backgroundA tissue-mimicking phantom that accurately represents human-tissue properties is important for safety testing and for validating new imaging techniques. To achieve a variety of desired human-tissue properties, we have fabricated and tested several variations of gelatin phantoms. These phantoms are simple to manufacture and have properties in the same order of magnitude as those of soft tissues. This is important for quality-assurance verification as well as validation of magnetic resonance-guided focused ultrasound (MRgFUS) treatment techniques.
methodsThe phantoms presented in this work were constructed from gelatin powders with three different bloom values (125, 175, and 250), each one allowing for a different mechanical stiffness of the phantom. Evaporated milk was used to replace half of the water in the recipe for the gelatin phantoms in order to achieve attenuation and speed of sound values in soft tissue ranges. These acoustic properties, along with MR (T1 and T2*), mechanical (density and Young's modulus), and thermal properties (thermal diffusivity and specific heat capacity), were obtained through independent measurements for all three bloom types to characterize the gelatin phantoms. Thermal repeatability of the phantoms was also assessed using MRgFUS and MR thermometry.
resultsAll the measured values fell within the literature-reported ranges of soft tissues. In heating tests using low-power (6.6 W) sonications, interleaved with high-power (up to 22.0 W) sonications, each of the three different bloom phantoms demonstrated repeatable temperature increases (10.4 ± 0.3 °C for 125-bloom, 10.2 ± 0.3 °C for 175-bloom, and 10.8 ± 0.2 °C for 250-bloom for all 6.6-W sonications) for heating durations of 18.1 s.
conclusionThese evaporated milk-modified gelatin phantoms should serve as reliable, general soft tissue-mimicking MRgFUS phantoms.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.