Evidence map›Paper›PMID 26146476›Full record

ArticleCognitive therapy and research2014

Medication Adherence and HIV Symptom Distress in Relation to Panic Disorder Among HIV-Positive Adults Managing Opioid Dependence.

Jesse D Kosiba, Adam Gonzalez, Conall O'Cleirigh, Steven A Safren

Open access · greenAbstract read
In one paragraph

Article in Cognitive therapy and research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Jesse D KosibaDepartment of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.
Adam GonzalezDepartment of Psychiatry and Behavioral Science, State University of New York at Stony Brook, Stony Brook, NY, USA.
Conall O'CleirighDepartment of Psychiatry, Massachusetts General Hospital, Boston, MA, USA; Department of Psychiatry, Harvard Medical School, Cambridge, MA, USA; The Fenway Institute, Boston, MA, USA.
Steven A SafrenDepartment of Psychiatry, Massachusetts General Hospital, Boston, MA, USA; Department of Psychiatry, Harvard Medical School, Cambridge, MA, USA; The Fenway Institute, Boston, MA, USA.
Massachusetts General Hospital · USHarvard University · USStony Brook University · US

Funding

CBT for depression &adherence in HIV methadone patientsR01DA018603 · NIDA · MASSACHUSETTS GENERAL HOSPITAL · PI SAFREN, STEVEN A · 2004 to 2008
$2.9M
Mind Body Treatment for WTC Responders with Comorbid PTSD and Respiratory IllnessU01OH010524 · OH · STATE UNIVERSITY NEW YORK STONY BROOK · PI BROMET, EVELYN J, GONZALEZ, ADAM · 2013 to 2015
$1.5M
Addressing psychosocial comorbidities in HIV treatment and preventionK24DA040489 · NIDA · UNIVERSITY OF MIAMI CORAL GABLES · PI SAFREN, STEVEN A · 2016 to 2020
$931k
Addressing psychosocial comorbidities in HIV treatment and preventionK24MH094214 · NIMH · UNIVERSITY OF MIAMI CORAL GABLES · PI SAFREN, STEVEN A · 2011 to 2015
$858k
Effects of Hurricane Sandy on the Respiratory and Mental Health of WTC RespondersR21ES023583 · NIEHS · STATE UNIVERSITY NEW YORK STONY BROOK · PI GONZALEZ, ADAM · 2013 to 2014
$388k
NIDA NIH HHS K24 DA040489NIDA NIH HHS R01 DA018603NIEHS NIH HHS R21 ES023583NIMH NIH HHS K24 MH094214NIOSH CDC HHS U01 OH010524
6 · The paper itself

Abstract

Panic disorder (PD) occurs at greater rates among those with HIV compared to those without HIV. Rates of PD may be elevated among those with opioid dependence (persons who inject drugs, PWID). Persons with HIV experience common bodily symptoms as a result of the disease and these symptoms overlap with those of PD which may contribute to a "fear of fear" cycle present in PD. HIV-positive, PWID represent an at-risk population in terms of poor medication adherence. HIV symptoms and HIV medication side-effects commonly overlap with panic symptoms and may affect HIV medication adherence. The aim of this investigation was to examine the impact of PD on HIV-related symptom distress and HIV medication adherence in HIV-positive adults (N = 131) in treatment for opioid use. Those with a diagnosis of PD evidenced greater levels of HIV symptom distress and lower levels of medication adherence than those without current PD. Results highlight the clinical importance of assessing for and treating PD among individuals with HIV that are prescribed antiretroviral therapy. Future work would benefit from examining observed associations longitudinally and identifying potential mechanisms involved.

Indexed as

AdherenceDistressHIVPanic disorderSubstance use

Identifiers

PMID26146476
PMCPMC4486286
OpenAlexW2077842737

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.