Evidence map›Paper›PMID 26146459›Full record

ArticleBehavioural neurology2015

Physical Feature Encoding and Word Recognition Abilities Are Altered in Children with Intractable Epilepsy: Preliminary Neuromagnetic Evidence.

Maria Pardos, Milena Korostenskaja, Jing Xiang, Hisako Fujiwara, Ki H Lee, Paul S Horn, Anna Byars, Jennifer Vannest, Yingying Wang, Nat Hemasilpin and 1 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Behavioural neurology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00600717 (Localizing Functional Brain Cortices and Epileptogenic Zones With High Frequency Brain Signals), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00600717 withdrawnnot on this map

Localizing Functional Brain Cortices and Epileptogenic Zones With High Frequency Brain Signals

TypeobservationalSponsorChildren's Hospital Medical Center, CincinnatiRan2000 to 2027Enrolled0ConditionsEpilepsy, Migraine, Headache, Pain
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Maria PardosDivision of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
Milena KorostenskajaDivision of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA ; Milena's Functional Brain Mapping and Brain-Computer Interface Lab, Florida Hospital for Children, Orlando, FL 32803, USA ; Comprehensive Pediatric Epilepsy Center, Florida Hospital for Children, Orlando, FL 32803, USA ; MEG Lab, Florida Hospital for Children, Orlando, FL 32803, USA.
Jing XiangDivision of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
Hisako FujiwaraDivision of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
Ki H LeeDivision of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA ; Comprehensive Pediatric Epilepsy Center, Florida Hospital for Children, Orlando, FL 32803, USA.
Paul S HornDivision of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA ; Division of Biostatistics & Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45299, USA.
Anna ByarsDivision of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
Jennifer VannestDivision of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA ; Pediatric Neuroimaging Research Consortium, Cincinnati Children's Hospital Research Foundation and Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
Yingying WangDivision of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA ; Biomedical Engineering, University of Cincinnati, Cincinnati, OH 45221, USA.
Nat HemasilpinDivision of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
Douglas F RoseDivision of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
Cincinnati Children's Hospital Medical Center · USAdventHealth for Children · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective evaluation of language function is critical for children with intractable epilepsy under consideration for epilepsy surgery. The purpose of this preliminary study was to evaluate word recognition in children with intractable epilepsy by using magnetoencephalography (MEG). Ten children with intractable epilepsy (M/F 6/4, mean ± SD 13.4 ± 2.2 years) were matched on age and sex to healthy controls. Common nouns were presented simultaneously from visual and auditory sensory inputs in "match" and "mismatch" conditions. Neuromagnetic responses M1, M2, M3, M4, and M5 with latencies of ~100 ms, ~150 ms, ~250 ms, ~350 ms, and ~450 ms, respectively, elicited during the "match" condition were identified. Compared to healthy children, epilepsy patients had both significantly delayed latency of the M1 and reduced amplitudes of M3 and M5 responses. These results provide neurophysiologic evidence of altered word recognition in children with intractable epilepsy.

Indexed as

LanguageAdolescentBrain MappingCerebral CortexChildEpilepsyFemaleHumansMagnetoencephalographyMaleMemoryTreatment Outcome

Identifiers

PMID26146459
PMCPMC4469800
OpenAlexW1565337221

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.