Evidence map›Paper›PMID 26143358›Full record

ArticleInternational journal of nursing studies2015

The association between breastfeeding, the stress response, inflammation, and postpartum depression during the postpartum period: Prospective cohort study.

Sukhee Ahn, Elizabeth J Corwin

Abstract read
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In one paragraph

Article in International journal of nursing studies, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 74 citations in OpenAlex.

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  16. The role of the immune system in postpartum psychosis.Brain, behavior, & immunity - health · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Sukhee AhnCollege of Nursing, Chungnam National University, Daejeon, Republic of Korea. Electronic address: sukheeahn@cnu.ac.kr.
Elizabeth J CorwinNell Hodgson Woodruff School of Nursing, Emory University, 1520 Clifton Road NE, Room 244, Atlanta, GA 30322, United States. Electronic address: ejcorwi@emory.edu.
Chungnam National University · KREmory University · US

Funding

Psychoneuroimmune Contributions to Postpartum DepressionR01NR011278 · NINR · UNIVERSITY OF COLORADO DENVER · PI CORWIN, ELIZABETH JEANNE · 2008 to 2012
$2.1M
NINR NIH HHS 1R01NR011278NINR NIH HHS R01 NR011278
6 · The paper itself

Abstract

backgroundResearch suggests that exclusive breastfeeding may have a stress-protective role in postpartum depression; however, less is known about the underlying mechanisms by which this protection may occur or whether the protective relationship holds for women who mix breast and bottle feeding.

objectivesTo examine patterns of the stress response, inflammation, and depressive symptoms among women predominantly breastfeeding or bottle feeding their infants at 6 months postpartum.

designA part of a larger longitudinal study across 6 months postpartum investigating the psychoneuroimmunology (PNI) of postpartum depression.

settingPrenatal clinics and community.

participantsOne hundred nineteen postpartum women who met inclusion/exclusion criteria and followed up from the prenatal period to postpartum 6 months.

methodsData were collected during seven home visits occurring during the 3rd trimester (weeks 32-36) and on postpartum days 7 and 14, months 1, 2, 3, and 6. Women completed stress and depression surveys and provided blood for pro- (IL-1β, IL-6, IL-8, TNF-a, IFN-γ) and anti-inflammatory (IL-10) cytokines, and collected saliva for diurnal cortisol.

resultsSelf-report of predominant breastfeeding during 6 months postpartum ranged from 91.9% at day 7 to 70.6% at month 6 postpartum. There were no associations between the pattern of feeding and depressive symptoms. Biological differences, however, existed between the groups, with levels of salivary cortisol at 8 AM and 8:30 AM at month 6 higher and levels of IL-6 at month 6 lower in women who primarily breastfed compared to those who primarily bottle fed their infants after controlling for confounding variables.

conclusionsBreastfeeding was not related to postpartum depression however differences in stress and inflammatory markers are apparent at month 6 postpartum.

Indexed as

Breast FeedingPostpartum PeriodAdultDepression, PostpartumFemaleHumansInflammationProspective StudiesStress, PsychologicalBreastfeedingDepressionInflammationPostpartumPsychoneuroimmunologyStress

Identifiers

PMID26143358
PMCPMC4540671
OpenAlexW1866674963

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.