ReviewCurrent treatment options in oncology2015
Current Management and Treatment Modalities for Intramedullary Spinal Cord Tumors.
Review in Current treatment options in oncology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 50 citations in OpenAlex.
- Minimally invasive approaches to intramedullary spinal cord tumors: a systematic review of techniques and outcomes.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Review
- Modified Hemilaminectomy for Bilateral Exposure in Intramedullary Spinal Cord Tumor Resection.Brain sciences · 2026Article
- Impact of Cigarette Smoking on Clinical Outcomes after Surgical Resection in Patients with Intramedullary Spinal Cord Tumors: A Retrospective Comparative Study.Spine surgery and related research · 2026Article
- Use of gross total resection and adjunctive therapy in treatment of spinal column tumors in low- and middle-income countries: A meta-analysis.Surgical neurology international · 2026Review
- Spinal ependymal tumors.Neuro-oncology advances · 2024Review
- Article
- Dorsal column mapping in resection of intramedullary spinal cord tumors: a prospective comparison of two methods and neurological follow-up.Acta neurochirurgica · 2023Article
- Outcomes of Intramedullary Spinal Cord Tumor Surgery in Older Versus Younger Adults: A Multicenter Subanalysis Study by the Neurospinal Society of Japan.Neurospine · 2023Article
- Malignant Spinal Tumors.Advances in experimental medicine and biology · 2023Article
- Case report: Surgical treatment of an astrocytoma in the thoracic spinal cord of a cat.Frontiers in veterinary science · 2023Article
- Current Trends in the Surgical Management of Intramedullary Tumors: A Multicenter Study of 1,033 Patients by the Neurospinal Society of Japan.Neurospine · 2022Article
- Spinal hemangioblastomas: analysis of surgical outcome and prognostic factors.Neurosurgical review · 2022Article
- Recurrence of cervical intramedullary gliofibroma.Spinal cord series and cases · 2021Article
- Stereotactic Radiation for Treating Primary and Metastatic Neoplasms of the Spinal Cord.Frontiers in oncology · 2020Review
- The role of 5-aminolevulinic acid in spinal tumor surgery: a review.Journal of neuro-oncology · 2019Review
- Magnetic Drug Targeting: A Novel Treatment for Intramedullary Spinal Cord Tumors.Scientific reports · 2018Article
- Preoperative steroids do not improve outcomes for intramedullary spinal tumors: a NSQIP analysis of 30-day reoperation and readmission rates.Journal of spine surgery (Hong Kong) · 2018Article
- Use of Intraoperative Ultrasound During Spinal Surgery.Global spine journal · 2017Article
- Adult pilocytic astrocytoma of conus medullaris: clinical considerations and review of the literature.CNS oncology · 2017Review
- Review of the History of Non-traumatic Spinal Cord Dysfunction.Topics in spinal cord injury rehabilitation · 2017Review
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
opinion statementIntramedullary spinal cord tumors are rare central nervous system tumors with unique challenges due to the eloquence of the surrounding tissue. Their treatment and prognosis is largely dependent on tumor histology and patient functionality. The introduction and advancement of microsurgical techniques have made surgery the mainstay of treatment for intramedullary tumors. Tumors that are well demarcated (e.g., ependymomas, hemangioblastomas) can be resected for cure, while more infiltrative tumors (e.g., high-grade astrocytomas) are typically managed with biopsies or limited resections in order to minimize the significant risk of damage to the spinal cord. The use of more aggressive surgical resection for astrocytoma is controversial but may have an increasing role in select cases. The use of intraoperative neurophysiologic monitoring and intraoperative ultrasound may help guide the extent of surgery while minimizing damage to normal tissue. Advances in MRI technology have greatly aided the diagnosis and preoperative planning of intramedullary tumors. Further advances in intraoperative MRI may make this a useful tool in guiding extent of resection. Preoperative functional status is the most important predictor of neurologic outcome, while histology and extent of resection are the most important predictors of progression-free survival. The use of adjuvant radiation and chemotherapy is dependent on patient age and histology but is largely reserved for high-grade tumor histologies or systemic involvement. Children are particularly at risk of radiation-induced injury, and these cases may benefit from more focused stereotactic radiation where necessary. Further studies are needed to support new surgical strategies minimizing destabilization and to investigate new forms of adjuvant therapy to minimize toxicity.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.