ArticlePlant physiology2015
HISTONE DEACETYLASE6-Defective Mutants Show Increased Expression and Acetylation of ENHANCER OF TRIPTYCHON AND CAPRICE1 and GLABRA2 with Small But Significant Effects on Root Epidermis Cellular Pattern.
Article in Plant physiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 35 citations in OpenAlex.
- HDA6 represses the histone acetylation modification and expression of WRKY18/40 to inhibit camalexin biosynthesis in Arabidopsis.Plant cell reports · 2026Article
- Regulatory mechanisms of trichome and root hair development in Arabidopsis.Plant molecular biology · 2024Review
- Roles of Histone Acetylation and Deacetylation in Root Development.Plants (Basel, Switzerland) · 2024Review
- Article
- GLABRA2, A Common Regulator for Epidermal Cell Fate Determination and Anthocyanin Biosynthesis inInternational journal of molecular sciences · 2019Review
- Histone Deacetylase HDA19 Affects Root Cortical Cell Fate by Interacting with SCARECROW.Plant physiology · 2019Article
- Establishment of Dimethyl Labeling-based Quantitative Acetylproteomics in Arabidopsis.Molecular & cellular proteomics : MCP · 2018Article
- Chromatin-Based Regulation of Plant Root Development.Frontiers in plant science · 2018Review
- Adaptor proteins GIR1 and GIR2. II. Interaction with the co-repressor TOPLESS and promotion of histone deacetylation of target chromatin.Biochemical and biophysical research communications · 2017Article
- Article
- The Histone Chaperone NRP1 Interacts with WEREWOLF to ActivateThe Plant cell · 2017Article
- An Inventory of Nutrient-Responsive Genes in Arabidopsis Root Hairs.Frontiers in plant science · 2016Article
- One additional histone deacetylase and 2 histone acetyltransferases are involved in cellular patterning of Arabidopsis root epidermis.Plant signaling & behavior · 2016Article
- Chromatin and Epigenetics.Plant physiology · 2015Article
- Cell Fate Determination and the Switch from Diffuse Growth to Planar Polarity in Arabidopsis Root Epidermal Cells.Frontiers in plant science · 2015Review
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cellular patterning in the Arabidopsis (Arabidopsis thaliana) root epidermis is dependent on positional information, the transmission of which involves histone acetylation. Here, we report that HISTONE DEACETYLASE6 (HDA6) has significant effects on this cellular patterning. Mutation of HDA6 led to ectopic hair cells in the nonhair positions of root epidermis in Arabidopsis, based on an analysis of paraffin sections stained with Toluidine Blue. While HDA6 was present throughout the root tip, epidermis-specific complementation with HDA6 could rescue the hda6 phenotype. Both transcript levels and expression patterns of ENHANCER OF TRIPTYCHON AND CAPRICE1 (ETC1) and GLABRA2 (GL2) in the root tip were affected in hda6. Consistent with these changes in expression, HDA6 directly bound to the promoter regions of ETC1 and GL2, and acetylation of histone H3 on these promoter regions and acetylation of histone H4 on the ETC1 promoter region was increased in the hda6 mutant. Taken together, these results indicate that HDA6 affects the cellular patterning of Arabidopsis root epidermis through altering the histone acetylation status of ETC1 and GL2 promoters and thereby affects the expression of these two components of the core transcription factor network determining epidermal cell fates. Our findings thus provide new insights into the role of histone acetylation in root epidermis cell patterning.
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