Evidence map›Paper›PMID 26143172›Full record

ArticleJournal of neurology2015

The association of aphasia and right-sided motor impairment in corticobasal syndrome.

Johannes Levin, Thomas H Bak, Axel Rominger, Erik Mille, Thomas Arzberger, Armin Giese, Nibal Ackl, Stefan Lorenzl, Benedikt Bader, Maximilian Patzig and 2 more

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Journal of neurology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Johannes LevinNeurology Department, Ludwig-Maximilians-Universität München, Marchioninistr. 15, 81377, Munich, Germany. johannes.levin@med.uni-muenchen.de.
Thomas H BakDepartment of Psychology and Centre for Clinical Brain Sciences, Edinburgh University, Edinburgh, UK.
Axel RomingerDepartment of Nuclear Medicine, Ludwig-Maximilians-Universität München, Munich, Germany.
Erik MilleDepartment of Nuclear Medicine, Ludwig-Maximilians-Universität München, Munich, Germany.
Thomas ArzbergerCenter for Neuropathology and Prion Research, Ludwig-Maximilians-Universität München, Munich, Germany.
Armin GieseCenter for Neuropathology and Prion Research, Ludwig-Maximilians-Universität München, Munich, Germany.
Nibal AcklNeurology Department, Ludwig-Maximilians-Universität München, Marchioninistr. 15, 81377, Munich, Germany.
Stefan LorenzlNeurology Department, Ludwig-Maximilians-Universität München, Marchioninistr. 15, 81377, Munich, Germany.
Benedikt BaderNeurology Department, Ludwig-Maximilians-Universität München, Marchioninistr. 15, 81377, Munich, Germany.
Maximilian PatzigDepartment of Neuroradiology, Ludwig-Maximilians-Universität München, Munich, Germany.
Kai BötzelNeurology Department, Ludwig-Maximilians-Universität München, Marchioninistr. 15, 81377, Munich, Germany.
Adrian DanekNeurology Department, Ludwig-Maximilians-Universität München, Marchioninistr. 15, 81377, Munich, Germany.
Ludwig-Maximilians-Universität München · DEUniversity of Edinburgh · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Corticobasal syndrome is defined clinically on the basis of symptoms and findings related to dysfunction of the cerebral cortex and the basal ganglia. Usually, marked asymmetry of motor findings is observed. Although aphasia has now been recognized as a frequent feature of corticobasal syndrome, it remains unclear whether it is usually associated with right-sided motor symptoms, pointing to the involvement of the left hemisphere. Hence, we set out to examine the relationship between the presence of language symptoms and the side affected by extrapyramidal symptoms. We analyzed the electronic care records of patients seen in the years 2003-2013 in the Neurology Department of the University Hospital of Munich. The diagnosis of corticobasal syndrome was discussed in ninety-two individuals. Of those, 38 cases fulfilled diagnostic criteria for corticobasal syndrome. Aphasia correlated highly with a predominant right-sided movement disorder (p = 0.002). In contrast, it was less common in patients with left-sided motor presentation. Dysarthria did not show a preferential correlation (p = 0.25). Our analysis suggests a characteristic presentation of corticobasal syndrome in which motor dysfunction of the right side of the body is associated with aphasia.

Indexed as

AdultAgedAged, 80 and overAphasiaBasal Ganglia DiseasesCerebral CortexDysarthriaFemaleFunctional LateralityHumansMaleMiddle AgedMovement DisordersAphasiaCorticobasal degenerationCorticobasal syndromeDementiaDysarthriaParkinsonism

Identifiers

PMID26143172
OpenAlexW2165426480

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.