ArticleGenome biology and evolution2015
Transcriptome Differences between Alternative Sex Determining Genotypes in the House Fly, Musca domestica.
Article in Genome biology and evolution, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Article
- Divergent evolution of male-determining loci on proto-Y chromosomes of the housefly.Nature communications · 2024Article
- Polygenic sex determination produces modular sex polymorphism in an African cichlid fish.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Thermal tolerance and preference are both consistent with the clinal distribution of house fly proto-Y chromosomes.Evolution letters · 2021Article
- How did the guppy Y chromosome evolve?PLoS genetics · 2021Article
- The genome of the stable fly, Stomoxys calcitrans, reveals potential mechanisms underlying reproduction, host interactions, and novel targets for pest control.BMC biology · 2021Article
- Sex Chromosome Evolution in Muscid Flies.G3 (Bethesda, Md.) · 2020Article
- Comparative genomic analysis of six Glossina genomes, vectors of African trypanosomes.Genome biology · 2019Article
- Minimal Effects of Proto-Genetics · 2019Article
- Functional Consequences of the Evolution of Matrimony, a Meiosis-Specific Inhibitor of Polo Kinase.Molecular biology and evolution · 2019Article
- De novo RNA-seq and functional annotation of Ornithonyssus bacoti.Experimental & applied acarology · 2018Article
- Review
- The house fly Y Chromosome is young and minimally differentiated from its ancient X Chromosome partner.Genome research · 2017Article
- CRISPR-Cas9 targeted disruption of the yellow ortholog in the housefly identifies the brown body locus.Scientific reports · 2017Article
- Article
- Repeated Duplication of Argonaute2 Is Associated with Strong Selection and Testis Specialization in Drosophila.Genetics · 2016Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Sex determination evolves rapidly, often because of turnover of the genes at the top of the pathway. The house fly, Musca domestica, has a multifactorial sex determination system, allowing us to identify the selective forces responsible for the evolutionary turnover of sex determination in action. There is a male determining factor, M, on the Y chromosome (Y(M)), which is probably the ancestral state. An M factor on the third chromosome (III(M)) has reached high frequencies in multiple populations across the world, but the evolutionary forces responsible for the invasion of III(M) are not resolved. To test whether the III(M) chromosome invaded because of sex-specific selection pressures, we used mRNA sequencing to determine whether isogenic males that differ only in the presence of the Y(M) or III(M) chromosome have different gene expression profiles. We find that more genes are differentially expressed between Y(M) and III(M) males in testis than head, and that genes with male-biased expression are most likely to be differentially expressed between Y(M) and III(M) males. We additionally find that III(M) males have a "masculinized" gene expression profile, suggesting that the III(M) chromosome has accumulated an excess of male-beneficial alleles because of its male-limited transmission. These results are consistent with the hypothesis that sex-specific selection acts on alleles linked to the male-determining locus driving evolutionary turnover in the sex determination pathway.
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