Evidence map›Paper›PMID 26142352›Full record

SynthesisNeuropsychologia2015

Specifying the core network supporting episodic simulation and episodic memory by activation likelihood estimation.

Roland G Benoit, Daniel L Schacter

Abstract readMeta-Analysis
In one paragraph

Synthesis in Neuropsychologia, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 168 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
168citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

168 citing papers in PubMed, 7 syntheses or guidelines pooled it.

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  4. Common and distinct correlates of construction and elaboration of episodic-autobiographical memory: An ALE meta-analysis.Cortex; a journal devoted to the study of the nervous system and behavior · 2023
    Pooled it
  5. Unveiling the neural underpinnings of optimism: a systematic review.Cognitive, affective & behavioral neuroscience · 2021
    Pooled it
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108 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Roland G BenoitDepartment of Psychology, Harvard University, Cambridge, MA 02138, USA; Center for Brain Science, Harvard University, Cambridge, MA 02138, USA. Electronic address: rbenoit@fas.harvard.edu.
Daniel L SchacterDepartment of Psychology, Harvard University, Cambridge, MA 02138, USA; Center for Brain Science, Harvard University, Cambridge, MA 02138, USA.

Funding

EVENT RELATED NEUROIMAGING OF HUMAN MEMORY FORMATIONR01MH060941 · NIMH · HARVARD UNIVERSITY · PI SCHACTER, DANIEL L · 2000 to 2025
$9.5M
NIMH NIH HHS R01 MH060941NIMH NIH HHS R01MH60941
6 · The paper itself

Abstract

It has been suggested that the simulation of hypothetical episodes and the recollection of past episodes are supported by fundamentally the same set of brain regions. The present article specifies this core network via Activation Likelihood Estimation (ALE). Specifically, a first meta-analysis revealed joint engagement of expected core-network regions during episodic memory and episodic simulation. These include parts of the medial surface, the hippocampus and parahippocampal cortex within the medial temporal lobes, and the temporal and inferior posterior parietal cortices on the lateral surface. Both capacities also jointly recruited additional regions such as parts of the bilateral dorsolateral prefrontal cortex. All of these core regions overlapped with the default network. Moreover, it has further been suggested that episodic simulation may require a stronger engagement of some of the core network's nodes as well as the recruitment of additional brain regions supporting control functions. A second ALE meta-analysis indeed identified such regions that were consistently more strongly engaged during episodic simulation than episodic memory. These comprised the core-network clusters located in the left dorsolateral prefrontal cortex and posterior inferior parietal lobe and other structures distributed broadly across the default and fronto-parietal control networks. Together, the analyses determine the set of brain regions that allow us to experience past and hypothetical episodes, thus providing an important foundation for studying the regions' specialized contributions and interactions.

Indexed as

Likelihood FunctionsMemory, EpisodicNeural PathwaysAgedBrainHumansImaginationMental RecallMiddle AgedCore networkEpisodic future thinkingEpisodic memoryEpisodic simulationFunctional MRIMeta analysis

Identifiers

PMID26142352
PMCPMC4546530

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.