ArticleEuropean journal of applied physiology2015
Local and remote thermoregulatory changes affect NIRS measurement in forearm muscles.
Article in European journal of applied physiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 19 citations in OpenAlex.
- Incongruous effect of phenylephrine on changes in cerebral blood volume measured by near-infrared spectroscopy (NIRS) indicating extracranial contamination.Journal of clinical monitoring and computing · 2022Trial
- Muscle oxygenation regulation in physical therapy and rehabilitation.Medical gas research · 2026Review
- Ischemic preconditioning: exploring local ergogenic mechanisms in non-fatiguing voluntary contractions.Frontiers in physiology · 2025Article
- Effects of ischemic pre-conditioning on electrically stimulated contractions.European journal of applied physiology · 2025Article
- Hemodynamic changes in the temporalis and masseter muscles during acute stress in healthy humans.European journal of applied physiology · 2024Article
- Article
- Evidence that large vessels do affect near infrared spectroscopy.Scientific reports · 2022Article
- Impact of cutaneous blood flow on NIR-DCS measures of skeletal muscle blood flow index.Journal of applied physiology (Bethesda, Md. : 1985) · 2021Article
- Hyper-Oxygenation Attenuates the Rapid Vasodilatory Response to Muscle Contraction and Compression.Frontiers in physiology · 2018Article
- Microvascular effects of intravenous esmolol in patients with normal cardiac function undergoing postoperative atrial fibrillation: a prospective pilot study in cardiothoracic surgery.Critical care (London, England) · 2017Observational
- An integrated view on the oxygenation responses to incremental exercise at the brain, the locomotor and respiratory muscles.European journal of applied physiology · 2016Review
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2 authors at 1 institution in 1 country.
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Abstract
purposeNear infrared spectroscopy (NIRS) assessment in skeletal muscle is potentially affected by circulatory changes occurring in superficial tissues. The aim of this study was to separately assess the interference from skin microcirculation and large vein blood flow by investigating the effect of selective local and remote warming-induced vasodilation, respectively.
methodsBlood volume and oxygenation changes were investigated in the forearm muscles of healthy subjects in two experimental series (ES) during selective forearm (ES1, n = 12) or hand warming (ES2, n = 10). In ES1, the response to muscle contraction (10 s, 70 % MVC) and occlusion before and after warming was also investigated, while in ES2 two NIRS probes were expressly positioned over a visible vein and over a vein-free area.
resultsLocal warming increased the modified Beer-Lambert (BL) blood volume indicator, tHb, by 5.3 ± 3.6 µmol/L cm to an extent comparable to post-contraction hyperemia (6.8 ± 2.9 µmol/L cm, p < 0.01). Remote warming increased skin blood flow at the hand and tHb at both forearm sites (on average: 5.4 ± 4.8 µmol/L cm, p < 0.01). Conversely, indicators of blood volume and oxygenation, based on spatially resolved spectroscopy (SRS), were not affected by any of the warming stimuli.
conclusionsThese results demonstrate for the first time that: (1) blood drained by superficial veins may affect BL measurement; (2) it is difficult to exclude veins from the measurement by simple visual inspection of the cutaneous surface; (3) SRS effectively rejects artifacts from superficial hemodynamic changes in both cutaneous microcirculation and large veins. These results bear implications to conditions in which thermoregulatory adjustments cannot be excluded.
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