Evidence map›Paper›PMID 26142266›Full record

Trial reportAtencion primaria2016

[Baseline characteristics and changes in treatment after a period of optimization of the patients included in the study EFICAR].

Manuel A Gómez-Marcos, Cristina Agudo-Conde, Jesús Torcal, Pilar Echevarria, Mar Domingo, María Arietaleanizbeascoa, Aitor Sanz-Guinea, Maria M de la Torre, Jose I Ramírez, Luis García-Ortiz and 1 more

Abstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Atencion primaria, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Manuel A Gómez-MarcosInstituto Investigación Biomédica Salamanca (IBSAL), Unidad Investigación de Atención Primaria, Centro de Salud Alamedilla, Servicio de Salud Castilla-León (SACYL), Salamanca, España; Departamento de Medicina, Universidad de Salamanca, Salamanca, España; redIAPP: Red de Investigación en Actividades Preventivas y Promoción de Salud, España. Electronic address: magomez@usal.es.
Cristina Agudo-CondeInstituto Investigación Biomédica Salamanca (IBSAL), Unidad Investigación de Atención Primaria, Centro de Salud Alamedilla, Servicio de Salud Castilla-León (SACYL), Salamanca, España; redIAPP: Red de Investigación en Actividades Preventivas y Promoción de Salud, España.
Jesús TorcalUnidad Investigación, Atención Primaria Bizkaia, Servicio Vasco de Salud-Osakidetza (SVSO), Bizkaia, España; Centro Salud Basauri-Ariz, SVSO, Bizkaia, España; redIAPP: Red de Investigación en Actividades Preventivas y Promoción de Salud, España.
Pilar EchevarriaCentro Salud de Galdakao, SVSO, Bizkaia, España; redIAPP: Red de Investigación en Actividades Preventivas y Promoción de Salud, España.
Mar DomingoCentro Salud de Sant Roc, Servicio Catalán de Salud, Badalona, Barcelona, España; redIAPP: Red de Investigación en Actividades Preventivas y Promoción de Salud, España.
María ArietaleanizbeascoaCentro Salud de Lutxana, SVSO, Bizkaia, España; redIAPP: Red de Investigación en Actividades Preventivas y Promoción de Salud, España.
Aitor Sanz-GuineaUnidad Investigación, Atención Primaria Bizkaia, Servicio Vasco de Salud-Osakidetza (SVSO), Bizkaia, España.
Maria M de la TorreCentro Salud Casa de Barco, SACYL, Valladolid, España; redIAPP: Red de Investigación en Actividades Preventivas y Promoción de Salud, España.
Jose I RamírezCentro Salud Calviá, Servicio de Salud Balear, Mallorca, España; Centro Salud Casa de Barco, SACYL, Valladolid, España.
Luis García-OrtizInstituto Investigación Biomédica Salamanca (IBSAL), Unidad Investigación de Atención Primaria, Centro de Salud Alamedilla, Servicio de Salud Castilla-León (SACYL), Salamanca, España; Departamento de Medicina, Universidad de Salamanca, Salamanca, España; redIAPP: Red de Investigación en Actividades Preventivas y Promoción de Salud, España.
EFICAR (Ejercicio Físico en IC)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo describe the baseline date and drugs therapy changes during treatment optimization in patients with heart failure with depressed systolic function included in the EFICAR study.

designMulticenter randomized clinical trial. LOCATION: Seven Health Centers.

participants150 patients (ICFSD) age 68±10 years, 77% male. MEASUREMENTS: Sociodemographic variables, comorbidities (Charlson index), functional capacity and quality of life. Drug therapy optimization was performed.

resultsThe main etiology was ischemic heart disease (45%), with 89% in functional class II. The Charlson index was 2.03±1.05. The ejection fraction mean was 37%±8, 19% with ejection fraction <30%. With the stress test 6.3±1.6 mean was reached, with the 6 minutes test 446±78 meters and the chair test 13.7±4.4 seconds. The overall quality of life with ejection fraction was 22.8±18.7 and with the Short Form-36 Health Survey, physical health 43.3±8.4 and mental health 50.1±10.6. After optimizing the treatment, the percentage of patients on drugs therapy and the dose of angiotensin converting enzyme inhibitors, angiotensin II receptor antagonists and beta-blockers were not changed.

conclusionsThe majority of the subjects are in functional class II, with functional capacity and quality of life decreased and comorbidity index high. A protocolized drug therapy adjustment did not increase the dose or number of patients with effective drugs for heart failure with depressed systolic function.

Indexed as

Adrenergic beta-AntagonistsAgedAngiotensin-Converting Enzyme InhibitorsComorbidityDrug Therapy, CombinationFemaleHealth StatusHeart FailureHumansMaleMiddle AgedQuality of LifeAdrenergic beta-AntagonistsAngiotensin-Converting Enzyme InhibitorsAtención primariaCalidad de vidaCapacidad funcionalFunctional capacityHeart failureInsuficiencia cardiacaPrimary careQuality of lifeTratamientoTreatment

Identifiers

PMID26142266
PMCPMC6877888

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.