Evidence map›Paper›PMID 26141960›Full record

ArticleMammalian genome : official journal of the International Mammalian Genome Society2015

Application of comparative biology in GO functional annotation: the mouse model.

Harold J Drabkin, Karen R Christie, Mary E Dolan, David P Hill, Li Ni, Dmitry Sitnikov, Judith A Blake

Open access · hybridAbstract read
In one paragraph

Article in Mammalian genome : official journal of the International Mammalian Genome Society, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Mouse genome database 2016.Nucleic acids research · 2016
    Article
  7. Orthology for comparative genomics in the mouse genome database.Mammalian genome : official journal of the International Mammalian Genome Society · 2015
    Review
  8. Mouse Genome Informatics (MGI): reflecting on 25 years.Mammalian genome : official journal of the International Mammalian Genome Society · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Harold J DrabkinThe Jackson Laboratory, Bar Harbor, ME, 04609, USA. harold.drabkin@jax.org.
Karen R ChristieThe Jackson Laboratory, Bar Harbor, ME, 04609, USA.
Mary E DolanThe Jackson Laboratory, Bar Harbor, ME, 04609, USA.
David P HillThe Jackson Laboratory, Bar Harbor, ME, 04609, USA.
Li NiThe Jackson Laboratory, Bar Harbor, ME, 04609, USA.
Dmitry SitnikovThe Jackson Laboratory, Bar Harbor, ME, 04609, USA.
Judith A BlakeThe Jackson Laboratory, Bar Harbor, ME, 04609, USA.
Jackson Laboratory · US

Funding

Shared Resource ManagementP30CA034196 · NCI · JACKSON LABORATORY · PI William Carl Skarnes · 1985 to 2026
$61.9M
Mouse Genome DatabaseU41HG000330 · NHGRI · JACKSON LABORATORY · PI BLAKE, JUDITH A, BULT, CAROL J · 2011 to 2020
$45.5M
Resource ProjectU41HG002273 · NHGRI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI THOMAS, PAUL D. · 2012 to 2021
$34.7M
Gene Ontology ConsortiumP41HG002273 · NHGRI · JACKSON LABORATORY · PI BLAKE, JUDITH A · 2004 to 2011
$27.4M
GENE ONTOLOGY CONSORTIUMR01HG002273 · NHGRI · JACKSON LABORATORY · PI BLAKE, JUDITH A · 2001 to 2003
$5.8M
NCI NIH HHS P30 CA034196NHGRI NIH HHS HG002273NHGRI NIH HHS P41 HG002273NHGRI NIH HHS R01 HG002273NHGRI NIH HHS U41 HG000330NHGRI NIH HHS U41 HG002273
6 · The paper itself

Abstract

The Gene Ontology (GO) is an important component of modern biological knowledge representation with great utility for computational analysis of genomic and genetic data. The Gene Ontology Consortium (GOC) consists of a large team of contributors including curation teams from most model organism database groups as well as curation teams focused on representation of data relevant to specific human diseases. Key to the generation of consistent and comprehensive annotations is the development and use of shared standards and measures of curation quality. The GOC engages all contributors to work to a defined standard of curation that is presented here in the context of annotation of genes in the laboratory mouse. Comprehensive understanding of the origin, epistemology, and coverage of GO annotations is essential for most effective use of GO resources. Here the application of comparative approaches to capturing functional data in the mouse system is described.

Indexed as

Databases, GeneticGene OntologyMolecular Sequence AnnotationAnimalsComputational BiologyGenomicsHumansMiceSequence Analysis, DNA

Identifiers

PMID26141960
PMCPMC4602061
OpenAlexW845874411

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.