Evidence map›Paper›PMID 26141788›Full record

SynthesisDiabetologia2015

Excessive gestational weight gain prior to glucose screening and the risk of gestational diabetes: a meta-analysis.

Stefanie Brunner, Lynne Stecher, Stephanie Ziebarth, Ina Nehring, Sheryl L Rifas-Shiman, Christine Sommer, Hans Hauner, Rüdiger von Kries

Open access · bronzeAbstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Diabetologia, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
85citing papers in PubMed, 4 pooled it
13.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

85 citing papers in PubMed, 4 syntheses or guidelines pooled it, 161 citations in OpenAlex.

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25 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Stefanie BrunnerElse Kröner-Fresenius-Centre for Nutritional Medicine, Klinikum Rechts der Isar, Technical University of Munich, Uptown Munich Campus D, Georg-Brauchle-Ring 60/62, 80992, Munich, Germany.
Lynne StecherElse Kröner-Fresenius-Centre for Nutritional Medicine, Klinikum Rechts der Isar, Technical University of Munich, Uptown Munich Campus D, Georg-Brauchle-Ring 60/62, 80992, Munich, Germany.
Stephanie ZiebarthDivision of Epidemiology, Institute of Social Pediatrics and Adolescent Medicine, Ludwig Maximilians University Munich, Munich, Germany.
Ina NehringDivision of Epidemiology, Institute of Social Pediatrics and Adolescent Medicine, Ludwig Maximilians University Munich, Munich, Germany.
Sheryl L Rifas-ShimanObesity Prevention Program, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA.
Christine SommerDepartment of Endocrinology, Morbid Obesity and Preventive Medicine, Oslo University Hospital, Oslo, Norway.
Hans HaunerElse Kröner-Fresenius-Centre for Nutritional Medicine, Klinikum Rechts der Isar, Technical University of Munich, Uptown Munich Campus D, Georg-Brauchle-Ring 60/62, 80992, Munich, Germany. hans.hauner@tum.de.
Rüdiger von KriesDivision of Epidemiology, Institute of Social Pediatrics and Adolescent Medicine, Ludwig Maximilians University Munich, Munich, Germany.
Ludwig-Maximilians-Universität München · DETechnical University of Munich · DEHarvard Pilgrim Health Care · USUniversity of Oslo · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aims/hypothesisExcessive gestational weight gain (GWG) may be a risk factor for gestational diabetes mellitus (GDM). We aimed to study the association between excessive GWG (defined according to Institute of Medicine recommendations) prior to GDM screening, and GDM.

methodsWe systematically searched four electronic databases from 1990 until September 2014 for observational studies published in English or German that reported an association between excessive GWG and GDM as the outcome. Random effects meta-analyses were performed to provide a pooled estimate of the OR comparing the risk of GDM in women with and without excessive GWG.

resultsA total of eight studies involving 13,748 participants were included. The pooled analysis of unadjusted OR yielded a summary OR of 1.40 (95% CI 1.21, 1.61; p < 0.001) with low between-study heterogeneity (I(2) = 16.7%). A sensitivity analysis based on four studies reporting adjusted effect estimates revealed similar results (OR 1.42; 95% CI 1.20, 1.68; p < 0.001; I(2) = 0%). No evidence was found that the effect of GWG on GDM differs depending on maternal pre-pregnancy BMI category. A funnel plot did not indicate substantial publication bias. CONCLUSIONS/

interpretationAvoiding excessive weight gain in pregnancy prior to the GDM screening test may be a potential strategy to reduce GDM risk. META-ANALYSIS REGISTRATION: www.crd.york.ac.uk/PROSPERO CRD42014008802.

Indexed as

Blood GlucoseDiabetes, GestationalFemaleGlucose Tolerance TestHumansPregnancyRisk FactorsWeight GainBlood GlucoseGDMGestational diabetesGestational weight gainIOM recommendationsMeta-analysisPregnancySystematic review

Identifiers

PMID26141788
OpenAlexW808432180

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.