ArticleJournal of genetic counseling2002
Genetic Counseling and Screening of Consanguineous Couples and Their Offspring: Recommendations of the National Society of Genetic Counselors.
Article in Journal of genetic counseling, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
63 citing papers in PubMed, 3 syntheses or guidelines pooled it, 237 citations in OpenAlex.
- Bartter Syndrome: A Systematic Review of Case Reports and Case Series.Medicina (Kaunas, Lithuania) · 2023Pooled it
- Consanguinity and the risk of congenital heart disease.American journal of medical genetics. Part A · 2012Pooled it
- Cystic fibrosis prenatal screening in genetic counseling practice: recommendations of the National Society of Genetic Counselors.Journal of genetic counseling · 2005Guideline
- Community-based behavioral change interventions to reduce the burden of inherited genetic disorders in low- and middle-income countries (LMICs): a scoping review.Journal of community genetics · 2026Review
- Association between parental consanguineous marriage and the incidence, age of onset, and severity of coronary artery disease: a cross-sectional study in Iran.Korean journal of family medicine · 2026Article
- Identification of a putative founder variant in SLC30A10 associated with hypermanganesemia with dystonia 1 in Iranian patients: a case series and literature review.BMC medical genomics · 2026Review
- Citywide premarital genomic screening in a Middle Eastern population.Nature medicine · 2026Article
- Metabolic and genetic spectrum of pediatric nephrolithiasis: insights from high-prevalence desert belt in India.Urolithiasis · 2026Observational
- Consanguinity in the Lebanese population: knowledge, attitudes and practices.Journal of community genetics · 2026Article
- Bi-allelic TPP1 variants in neuronal ceroid lipofuscinosis 2: clinical findings from an Iranian cohort of 20 patients, founder effect, and in silico analyses.Human genetics · 2026Article
- Genealogical Identification and Short Tandem Repeat-Based Verification of Suspected Consanguinity in Mongolian Families.The application of clinical genetics · 2026Article
- Outcomes of human leukocyte antigen matched sibling transplant from consanguineous versus non-consanguineous parents, a single center experience.Bone marrow transplantation · 2025Article
- Assessing and attending to psychosocial concerns in genetic counseling: Proposing the BATHE method.Journal of genetic counseling · 2025Article
- Effectiveness of expanded prenatal screening among consanguineous couples of Afghan descent.AJOG global reports · 2025Article
- Case Report: Simultaneous presentation of end-stage heart failure with cardiogenic shock requiring emergency transplantation in monozygotic twins with myofibrillar myopathy: a previously unknown genetic disease?Frontiers in cardiovascular medicine · 2025Article
- Primary sex ratio in euploid embryos of consanguine couples after IVF/ICSI.Journal of assisted reproduction and genetics · 2024Article
- Consanguineous Marriage and Its Association With Genetic Disorders in Saudi Arabia: A Review.Cureus · 2024Review
- Promoting international, locally focused, and patient-oriented genetic counseling.Genetics in medicine open · 2024Article
- Features of chromosomal abnormalities in relation to consanguinity: analysis of 10,556 blastocysts from IVF/ICSI cycles with PGT-A from consanguineous and non-consanguineous couples.Scientific reports · 2023Article
- Assessment of Perceptions and Predictors Towards Consanguinity: A Cross-Sectional Study from Palestine.Journal of multidisciplinary healthcare · 2023Article
3 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 8 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The objective of this document is to provide recommendations for genetic counseling and screening for consanguineous couples (related as second cousins or closer) and their offspring with the goals of1. providing preconception reproductive options2. improving pregnancy outcome and identifying reproductive choices3. reducing morbidity and mortality in the 1st years of life, and4. respecting psychosocial and multicultural issues.The recommendations are the opinions of a multicenter working group (the Consanguinity Working Group (CWG)) with expertise in genetic counseling, medical genetics, biochemical genetics, genetic epidemiology, pediatrics, perinatology, and public health genetics, which was convened by the National Society of Genetic Counselors (NSGC). The consensus of the CWG and NSGC reviewers is that beyond a thorough medical family history with follow-up of significant findings, no additional preconception screening is recommended for consanguineous couples. Consanguineous couples should be offered similar genetic screening as suggested for any couple of their ethnic group. During pregnancy, consanguineous couples should be offered maternal-fetal serum marker screening and high-resolution fetal ultrasonography. Newborns should be screened for impaired hearing and detection of treatable inborn errors of metabolism. These recommendations should not be construed as dictating an exclusive course of management, nor does use of such recommendations guarantee a particular outcome. The professional judgment of a health care provider, familiar with the facts and circumstances of a specific case, will always supersede these recommendations.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.