Evidence map›Paper›PMID 26141450›Full record

ArticleComparative medicine2015

Use of Femoral Head and Neck Ostectomy and Physical Therapy to Manage Osteoarthritis in a Rhesus Macaque (Macaca mulatta).

Mayu Uchihashi, Joseph A Hampel, Jean A Nemzek, Phillip A Saccone, Kathryn A Eaton, Megan H Nowland

Open access · greenAbstract read
In one paragraph

Article in Comparative medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 76% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Mayu UchihashiUniversity of Michigan, Unit for Laboratory Animal Medicine. Ann Arbor, Michigan, USA. mayu.uchihashi@gmail.com.
Joseph A HampelMPI Research. Mattawan, Michigan, USA.
Jean A NemzekUniversity of Michigan, Unit for Laboratory Animal Medicine. Ann Arbor, Michigan, USA.
Phillip A SacconeUniversity of Michigan, Department of Pharmacology. Ann Arbor, Michigan, USA.
Kathryn A EatonUniversity of Michigan, Unit for Laboratory Animal Medicine. Ann Arbor, Michigan, USA.
Megan H NowlandUniversity of Michigan, Unit for Laboratory Animal Medicine. Ann Arbor, Michigan, USA.
University of Michigan · USMPI Research (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteoarthritis is associated with pain and immobility in both humans and animals. However, available resources for osteoarthritis management in captive NHP are limited. This case report describes a novel management strategy for a 10-y-old male macaque with unilateral hindlimb lameness, prominent muscle wasting, and severely limited range of motion. Radiographs of the affected limb showed lytic lesions of the femoral head. To relieve pain and improve mobility, femoral head and neck ostectomy (FHO) was performed, and multiple pharmacotherapies were initiated. The macaque also received a unique method of physical therapy that required no sedation, acted as enrichment, and was implemented by using a conventional caging system. The response to therapy was monitored by measuring thigh circumference in the operated and nonoperated limbs, which demonstrated improvement in both legs. The unique physical therapy in conjunction with surgery and pharmacotherapy benefited the macaque with osteoarthritis by reducing discomfort and improving mobility.

Indexed as

AnimalsAnti-Inflammatory Agents, Non-SteroidalFemur HeadFemur NeckFish OilsMacaca mulattaMaleOsteoarthritisPhysical Therapy ModalitiesPostoperative CareAnti-Inflammatory Agents, Non-SteroidalFish Oils

Identifiers

PMID26141450
PMCPMC4485634
OpenAlexW2410905003

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.