ArticleMayo Clinic proceedings2015
Incidence of Infective Endocarditis Due to Viridans Group Streptococci Before and After the 2007 American Heart Association's Prevention Guidelines: An Extended Evaluation of the Olmsted County, Minnesota, Population and Nationwide Inpatient Sample.
Article in Mayo Clinic proceedings, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 68 citations in OpenAlex.
- The effect of interventions aiming to optimise the prescription of antibiotics in dental care-A systematic review.PloS one · 2017Pooled it
- Epidemiology of infective endocarditis beforeTherapeutic advances in cardiovascular diseasePooled it
- Microbial Transitions in Infective Endocarditis Influence the Spectrum of Clinical Features and Functional Outcomes.Circulation reports · 2025Article
- A polymicrobial perspective into the ecological role of Enterococcus faecalis in dental root canal infections.NPJ biofilms and microbiomes · 2025Review
- Mapping Review of the Correlations Between Periodontitis, Dental Caries, and Endocarditis.Dentistry journal · 2025Review
- Global Trends and Regional Differences in the Burden of Infective Endocarditis, 1990-2021: An Analysis of the Global Burden of Disease Study 2021.Journal of epidemiology and global health · 2025Article
- Increase in Oral Streptococcal Endocarditis Among Moderate-Risk Patients: Impact of Guideline Changes on Endocarditis Prevention.JACC. Advances · 2024Article
- Prediction of Diagnosis-Related Groups for Appendectomy Patients Using C4.5 and Neural Network.Healthcare (Basel, Switzerland) · 2023Article
- Infective endocarditis: association between origin of causing bacteria and findings during oral infection screening.BMC oral health · 2022Article
- Functional screening of a human saliva metagenomic DNA reveal novel resistance genes against sodium hypochlorite and chlorhexidine.BMC oral health · 2021Article
- Temporal Trends of Infective Endocarditis in Olmsted County, Minnesota, Between 1970 and 2018: A Population-Based Analysis.Open forum infectious diseases · 2021Article
- The New Challenge for Heart Endocarditis: From Conventional Prosthesis to New Devices and Platforms for the Treatment of Structural Heart Disease.BioMed research international · 2021Review
- Infective endocarditis in the 21st century.Annals of translational medicine · 2020Article
- A narrative review of the interpretation of guidelines for the treatment of infective endocarditis.Annals of translational medicine · 2020Review
- The epidemiological and clinical features of odontogenic infective endocarditis.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2020Article
- Infective endocarditis: innovations in the management of an old disease.Nature reviews. Cardiology · 2019Review
- Article
- Incidence, characteristics, and mortality of infective endocarditis in France in 2011.PloS one · 2019Article
- Effect of the American Heart Association 2007 Guidelines on the Practice of Dental Prophylaxis for the Prevention of Infective Endocarditis in Olmsted County, Minnesota.Mayo Clinic proceedings · 2017Article
- The Changing Epidemiology of Infective Endocarditis in the Twenty-First Century.Current infectious disease reports · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
Abstract
objectiveTo determine whether the incidence of infective endocarditis (IE) due to viridans group streptococci (VGS) increased after the publication of the 2007 American Heart Association (AHA) IE prevention guidelines. PATIENTS AND
methodsWe performed a population-based survey of all adults (18 years and older) residing in Olmsted County, Minnesota, from January 1, 1999, through December 31, 2013, to identify definite or possible cases of VGS-IE using the Rochester Epidemiology Project. The National (Nationwide) Inpatient Sample hospital discharge database was examined to determine the number of VGS-IE cases in the United States between 2000 and 2011.
resultsRates of incidence (per 100,000 person-years) during the intervals of 1999-2002, 2003-2006, 2007-2010, and 2011-2013 were 3.6 (95% CI, 1.3-5.9), 2.7 (95% CI, 0.9-4.4), 0.7 (95% CI, 0.0-1.6), and 1.5 (95% CI, 0.2-2.9), respectively, reflecting an overall significant decrease (P=.03 from Poisson regression). Likewise, nationwide estimates of hospital discharges with a VGS-IE diagnosis trended downward during 2000-2011, with a mean number per year of 15,853 and 16,157 for 2000-2003 and 2004-2007, respectively, decreasing to 14,231 in 2008-2011 (P=.05 from linear regression using weighted least squares method).
conclusionDespite major reductions in the number of indications for antibiotic prophylaxis for invasive dental procedures espoused by the 2007 AHA IE prevention guidelines, both local and national data indicate that the incidence of VGS-IE has not increased.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.