ArticleBMC genomics2015
Horizontal gene transfer in an acid mine drainage microbial community.
Article in BMC genomics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 30 citations in OpenAlex.
- Genome-resolved metagenomics and evolutionary analysis reveal conserved metabolic adaptations in extremophile communities from a copper mining tailing.Environmental microbiome · 2025Article
- Roles of mobile genetic elements and biosynthetic gene clusters in environmental adaptation of acidophilic archaeonFrontiers in microbiology · 2025Article
- Insertion sequence contributes to the evolution and environmental adaptation of Acidithiobacillus.BMC genomics · 2023Article
- The interaction between gut microbiome and anti-tumor drug therapy.American journal of cancer research · 2021Review
- metaFlye: scalable long-read metagenome assembly using repeat graphs.Nature methods · 2020Article
- Characterization of an acid rock drainage microbiome and transcriptome at the Ely Copper Mine Superfund site.PloS one · 2020Article
- Current and Promising Approaches to Identify Horizontal Gene Transfer Events in Metagenomes.Genome biology and evolution · 2019Review
- Identification of an Autorepressing Two-Component Signaling System That Modulates Virulence in Streptococcus suis Serotype 2.Infection and immunity · 2019Article
- How Microbes Shape Their Communities? A Microbial Community Model Based on Functional Genes.Genomics, proteomics & bioinformatics · 2019Article
- MetaComp: comprehensive analysis software for comparative meta-omics including comparative metagenomics.BMC bioinformatics · 2017Article
- Article
- Biology of archaea from a novel family Cuniculiplasmataceae (Thermoplasmata) ubiquitous in hyperacidic environments.Scientific reports · 2016Article
- Metagenomics and Bioinformatics in Microbial Ecology: Current Status and Beyond.Microbes and environments · 2016Review
- Global biogeography of Prochlorococcus genome diversity in the surface ocean.The ISME journal · 2016Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHorizontal gene transfer (HGT) has been widely identified in complete prokaryotic genomes. However, the roles of HGT among members of a microbial community and in evolution remain largely unknown. With the emergence of metagenomics, it is nontrivial to investigate such horizontal flow of genetic materials among members in a microbial community from the natural environment. Because of the lack of suitable methods for metagenomics gene transfer detection, microorganisms from a low-complexity community acid mine drainage (AMD) with near-complete genomes were used to detect possible gene transfer events and suggest the biological significance.
resultsUsing the annotation of coding regions by the current tools, a phylogenetic approach, and an approximately unbiased test, we found that HGTs in AMD organisms are not rare, and we predicted 119 putative transferred genes. Among them, 14 HGT events were determined to be transfer events among the AMD members. Further analysis of the 14 transferred genes revealed that the HGT events affected the functional evolution of archaea or bacteria in AMD, and it probably shaped the community structure, such as the dominance of G-plasma in archaea in AMD through HGT.
conclusionsOur study provides a novel insight into HGT events among microorganisms in natural communities. The interconnectedness between HGT and community evolution is essential to understand microbial community formation and development.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.