Evidence map›Paper›PMID 26140931›Full record

ArticleThe American journal of hospice & palliative care2016

Initial Development of a Computer Algorithm to Identify Patients With Breast and Lung Cancer Having Poor Prognosis in a Safety Net Hospital.

Ramona L Rhodes, Sabiha Kazi, Lei Xuan, Ruben Amarasingham, Ethan A Halm

Abstract read
In one paragraph

Article in The American journal of hospice & palliative care, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ramona L RhodesDivision of Geriatric Medicine, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA ramona.rhodes@utsouthwestern.edu.
Sabiha KaziDepartment of Medicine, Weill Cornell Medical College, New York, NY, USA.
Lei XuanDepartment of Clinical Sciences, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Ruben AmarasinghamParkland Center for Clinical Innovation, Dallas, TX, USA Division of General Internal Medicine, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Ethan A HalmDepartment of Clinical Sciences, University of Texas Southwestern Medical Center, Dallas, TX, USA Division of General Internal Medicine, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA.

Funding

UT Southwestern Center for Translational Medicine (UL1/KL2/TL1)UL1TR001105 · NCATS · UT SOUTHWESTERN MEDICAL CENTER · PI TOTO, ROBERT DANIEL · 2013 to 2017
$24.5M
UT-Southwestern Clinical and Translational Alliance for Research (UT-STAR) (TL1)KL2TR000453 · NCATS · UT SOUTHWESTERN MEDICAL CENTER · PI TOTO, ROBERT DANIEL · 2012 to 2012
$456k
AHRQ HHS R24 HS022418NCATS NIH HHS KL2 TR000453NCATS NIH HHS UL1 TR001105
6 · The paper itself

Abstract

backgroundPhysicians often have difficulty with prognostication and identification of patients who are in need of counseling about options for care at the end of life. Consequently, the objective of this study was to describe the initial stages in development of a computerized algorithm that will identify breast and lung cancer patients most in need of counseling about care options, including advance care planning, palliative care, and hospice.

methodsClinical and non-clinical data were extracted from the electronic medical record of breast and lung cancer patients admitted to a large, urban hospital for the year 2010. These data were used to create an electronic (e-EOL) algorithm designed to identify advanced cancer patients who could benefit from in-depth discussion about end-of-life care options.

resultsThere were 369 eligible breast (42%) and lung (58%) cancer patients identified by ICD-9 code. The e-EOL algorithm identified 53 (14%) patients that met assigned criteria (presence of metastatic disease and albumin < 2.5 g/dl). The sensitivity, specificity, and positive predictive value of the first generation algorithm were 21%, 96%, and 91% when compared to physician expert chart review. Survival analysis showed that 6-month survival for algorithm positive cases was 46% versus 78% for algorithm negative cases, and 1-year survival was 32% versus 72%, respectively.

conclusionsInitial testing of the e-EOL algorithm appears to be promising. Other markers of advanced illness will added to the algorithm to improve its test operating characteristics so it may be used to identify patients with poor prognosis in real time.

Indexed as

AlgorithmsDecision Making, Computer-AssistedAdvance Care PlanningBreast NeoplasmsElectronic Health RecordsEmergency Service, HospitalHospice CareHospitalizationHospitals, UrbanHumansLung NeoplasmsMaleMiddle AgedPalliative CarePredictive Value of TestsPrognosisSerum Albumincancerelectronic medical recordend-of-life carehealth information technologypalliative careprognosissafety net

Identifiers

PMID26140931
PMCPMC7292337

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.