Evidence map›Paper›PMID 26140867›Full record

SynthesisSleep medicine reviews2016

Risk factors for sleep disturbances in older adults: Evidence from prospective studies.

Stephen F Smagula, Katie L Stone, Anthony Fabio, Jane A Cauley

Abstract readSystematic Review
In one paragraph

Synthesis in Sleep medicine reviews, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 147 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
147citing papers in PubMed, 10 pooled it
23.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

147 citing papers in PubMed, 10 syntheses or guidelines pooled it, 341 citations in OpenAlex.

  1. Pooled it
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  5. Smoking and risk of sleep-related issues: a systematic review and meta-analysis of prospective studies.Canadian journal of public health = Revue canadienne de sante publique · 2020
    Pooled it
  6. Pooled it
  7. Sleep and frailty risk: a systematic review and meta-analysis.Sleep & breathing = Schlaf & Atmung · 2020
    Pooled it
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  11. Effects of motivational music on sleep quality for caregivers of patients with advanced cancer: a randomized controlled trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Trial
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  17. Bidirectional causal association between frailty and six psychiatric disorders.European archives of psychiatry and clinical neuroscience · 2026
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  20. Review

87 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Stephen F SmagulaDepartment of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA.
Katie L StoneResearch Institute, California Pacific Medical Center, San Francisco, CA, USA.
Anthony FabioDepartment of Epidemiology, Epidemiology Data Center, University of Pittsburgh, Pittsburgh, PA, USA.
Jane A CauleyDepartment of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address: jcauley@edc.pitt.edu.
University of Pittsburgh · USCalifornia Pacific Medical Center · US

Funding

TRAINING IN THE EPIDEMIOLOGY OF AGINGT32AG000181 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI STROTMEYER, ELSA S. · 1989 to 2025
$6.2M
NIA NIH HHS T32 AG000181
6 · The paper itself

Abstract

No systematic review of epidemiological evidence has examined risk factors for sleep disturbances among older adults. We searched the PubMed database combining search terms targeting the following domains 1) prospective, 2) sleep, and 3) aging, and identified 21 relevant population-based studies with prospective sleep outcome data. Only two studies utilized objective measures of sleep disturbance, while six used the Pittsburgh sleep quality index (PSQI) and thirteen used insomnia symptoms or other sleep complaints as the outcome measure. Female gender, depressed mood, and physical illness were most consistently identified as risks for future sleep disturbances. Less robust evidence implicated the following as potentially relevant predictors: lower physical activity levels, African-American race, lower economic status, previous manual occupation, widowhood, marital quality, loneliness and perceived stress, preclinical dementia, long-term benzodiazepine and sedative use, low testosterone levels, and inflammatory markers. Chronological age was not identified as a consistent, independent predictor of future sleep disturbances. In conclusion, prospective studies have identified female gender, depressed mood, and physical illness as general risk factors for future sleep disturbances in later life, although specific physiological pathways have not yet been established. Research is needed to determine the precise mechanisms through which these factors influence sleep over time.

Indexed as

Sleep Wake DisordersAgedAgingFemaleHumansMaleProspective StudiesRisk FactorsSex DistributionAgingInsomniaProspective researchRisk factorsSleep disturbanceSleep quality

Identifiers

PMID26140867
PMCPMC4506260
OpenAlexW2057546532

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.